THIOCOLCHICOSIDE
2026-04-14
产品详情
- Cas：602-41-5
- 产品名称THIOCOLCHICOSIDE
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- 简介
| Test Item | Specification |
| Assay (HPLC) | ≥98.0% (Pharma grade ≥99.0%) |
| Appearance | Yellow to yellowish-brown powder, uniform |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.5% |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic (As) | ≤2 ppm |
| Single Impurity | ≤1.0% |
| Total Impurities | ≤2.0% |
| IR Identification | Conforms to reference standard |
- CAS No.：602-41-5
- Name：Thiocolchicoside
- Synonyms：Thiocolchicoside (98%), Coltramyl, 10-Thiocolchicoside
- Formula：C27H33NO10S
- Molecular Weight：563.62
- EINECS：210-017-7
Pharmaceutical (Primary Use)
- Muscle Relaxant：Potently relieves skeletal muscle spasms for neck/shoulder/low back pain, sciatica, and fibromyalgia.
- Analgesic & Anti-inflammatory：Inhibits inflammatory mediators; effective pain relief with fewer side effects than colchicine.
- Rheumatic Disorders：Adjuvant therapy for rheumatoid arthritis, ankylosing spondylitis, and chronic pain.
- Dosage Forms：Oral tablets, injections, topical gels/creams (lower toxicity for topical use).
2. Pharmaceutical Synthesis Intermediate
- Key intermediate for colchicine derivatives; used in novel anti-tumor and anti-inflammatory drug synthesis.
- Sulfur ether bond construction and functional group transformation in peptides and small-molecule drugs.
3. Veterinary Use
- Analgesic and muscle relaxant for animal musculoskeletal disorders (e.g., joint pain, soft tissue injuries in horses and dogs).
- Hazards：Acute toxicity category 3 (oral/inhalation) – H301: Harmful if swallowed; H331: Harmful if inhaled.
- Contraindications：Contraindicated in pregnancy/lactation; use caution in hepatic/renal impairment; avoid combination with central nervous system depressants.
- Protection：Wear dust mask, goggles, chemical gloves; ensure adequate ventilation.
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