Purity by gas chromatography not less than 98.0%.
Moisture content no more than 0.5%.
Residue on ignition not more than 0.1%.
Heavy metals content less than 10 ppm.
Melting point range complies with 131–135 °C specification, no obvious impurity peak detected.
This compound is a critical halogenated imidazopyridine heterocyclic building block, widely applied in pharmaceutical chemistry and organic synthesis. It serves as key intermediate for the synthesis of kinase inhibitors including JAK, CDK and BTK series, used in anti-tumor and autoimmune disease drug development. It can also be used to prepare GPCR receptor modulators for central nervous system and anti-inflammatory drug research.
With dibromo-chloro substituted structure, it is suitable for Suzuki, Heck, Buchwald-Hartwig and Sonogashira cross-coupling reactions. It is commonly used for compound library construction and SAR structure-activity relationship research in medicinal chemistry, and can also be used to synthesize imidazopyridine fluorescent probes for biological imaging and antibacterial lead compound screening.
...
Product
