The product is white to off-white crystalline solid.
Purity analyzed by HPLC is not less than 98.0%.
Water content is no more than 0.5%.
Residue on ignition is not more than 0.1%.
Heavy metals content is lower than 10 ppm.
No obvious impurity peaks appear in chromatogram, all indicators meet pharmaceutical intermediate grade standard.
2,5-Dibromopyridine is an important dihalogenated pyridine synthetic building block.
It owns two reactive bromine atoms at different positions on the pyridine ring, allowing selective stepwise cross-coupling reactions.
It can be applied in Suzuki, Heck, Sonogashira and Buchwald-Hartwig amination reactions for molecular modification.
It is widely used as key intermediate in the synthesis of kinase inhibitors, anticancer drugs, anti-inflammatory agents and central nervous system therapeutic molecules.
Also used for medicinal chemistry compound library construction and structure-activity relationship research, as well as agrochemical and fine chemical synthesis.
...
Product
