The product is a white to off-white crystalline solid.
Purity by HPLC ≥ 98.0%.
Water content ≤ 0.5%.
Residue on ignition ≤ 0.1%.
Heavy metals < 10 ppm.
No significant impurity peaks detected, conforms to pharmaceutical impurity reference standard grade.
1-(3-Ethyl-4-(hydroxymethyl)phenyl)ethan-1-one is a key pharmaceutical intermediate and impurity reference standard for Siponimod (BAF-312), a selective S1P receptor modulator.
It serves as a critical synthetic building block in the production of Siponimod and its salts/solid forms.
Widely applied in impurity profiling, method validation, and quality control for Siponimod drug substance and finished dosage forms.
Used in medicinal chemistry research for structure-activity relationship (SAR) studies and synthetic route optimization of S1P modulators.
Also utilized as a reference standard in pharmacokinetic and toxicological studies of Siponimod. 
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