9-Bromo-3-(2-Bromo Acetyl)-10,11-Dihydro-5H-dibenzo(c,g) Chromen-8(9H)-one
2026-04-14
产品详情
- Cas:1438383-89-1
- 产品名称9-Bromo-3-(2-Bromo Acetyl)-10,11-Dihydro-5H-dibenzo(c,g) Chromen-8(9H)-one
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- 简介
- Purity (HPLC): ≥97.0% / ≥99.0%
- Moisture: ≤0.30%
- Loss on Drying: ≤0.40%
- Residue on Ignition: ≤0.10%
- Single Impurity: ≤0.50%
- Total Impurities: ≤1.00%
- Heavy Metals (Pb): ≤10 ppm
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Velpatasvir (Anti-HCV Drug) Key Intermediate (Core Use)
Critical building block for synthesizing
Velpatasvir, a direct-acting antiviral agent against hepatitis C virus (HCV). It undergoes cyclization, substitution, and coupling reactions to construct the core dibenzochromenone scaffold of Velpatasvir, ensuring high potency and broad genotype coverage for HCV treatment.
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Antiviral Pharmaceutical Intermediate
Used in the synthesis of other antiviral drugs targeting RNA viruses (e.g., HCV, dengue, Zika); the dibenzochromenone core enhances binding to viral non-structural proteins (NS5A/NS5B).
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Heterocyclic Chemistry Building Block
Serves as a precursor for complex fused-ring systems via nucleophilic substitution (bromo groups) and carbonyl condensation; widely applied in synthetic methodology for polycyclic aromatic compounds.
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Laboratory Research & Reference Standard
Employed in pharmaceutical R&D, impurity profiling, and as a reference standard for HPLC analysis in antiviral drug development.
- Storage: Sealed, cool (2–8 °C), dry, dark, and ventilated; avoid light, moisture, and strong oxidants
- Packaging: 1g/5g/10g/25g aluminum foil bags or glass bottles; 10mg/25mg/50mg for lab use
- Shelf Life: 24 months under proper storage


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