Assay (GC/Nonaqueous Liquid Titration)≥98.0% (area %); industrial grade ≥95.0%
Appearance White to pale yellow or pale reddish crystalline powder
Melting Point 53–58 °C
Loss on Drying (Water Content)≤0.5%
Residue on Ignition≤0.1%
Heavy Metals (Pb)≤10 ppm
Impurities Single impurity ≤0.2%, total impurities ≤1.0% (for ≥98.0% purity)
Identification Consistent with the standard (IR/UV/GC)
4. Main Applications (Detailed)
3,5-Dimethoxyaniline (CAS 10272-07-8) is an important aromatic amine compound with two methoxy groups and an amino group on the benzene ring, which endows it with good reactivity and versatility. It is widely used as an intermediate in organic synthesis, pharmaceutical, fine chemical, and other fields.
4.1 Organic Synthesis Intermediate
It is a key building block in organic synthesis, mainly used for the preparation of various aromatic derivatives through diazotization, acylation, and condensation reactions. The amino group on its molecular structure can undergo diazotization reactions to form diazonium salts, which are further used in coupling reactions to synthesize azo dyes, pigments, and other compounds. The methoxy groups can be modified to introduce other functional groups, making it an important intermediate for the synthesis of heterocyclic compounds (such as pyrazoles, triazoles) and specialty organic chemicals.
4.2 Pharmaceutical Intermediate
As an important pharmaceutical intermediate, it is widely used in the synthesis of various drugs, including antibacterial, antiviral, anti-inflammatory, and anti-tumor drugs. Its unique molecular structure can be modified to synthesize drug molecules with specific biological activities, such as modifying the amino group to improve the solubility and bioavailability of drugs. It is also used in the synthesis of pharmaceutical intermediates such as 3,5-dimethoxybenzoyl derivatives, which are widely used in the research and development of new drugs.
4.3 Fine Chemical and Dye Industry
In the fine chemical industry, it is used in the production of specialty chemicals, such as organic catalysts, corrosion inhibitors, and plastic additives. In the dye industry, it is used as an intermediate for the synthesis of disperse dyes, acid dyes, and reactive dyes, which are widely used in the dyeing of textiles, leather, and plastics. The methoxy groups in its structure can enhance the color fastness and brightness of dyes, improving the quality of dyed products.
4.4 Laboratory Research Reagent
In scientific research, it is used as a research reagent in organic chemistry, analytical chemistry, and biochemistry laboratories. It is utilized in the development of new synthetic methodologies, the study of reaction mechanisms, and the detection of specific functional groups. It is also used as a standard substance for analytical detection (such as HPLC and GC) to verify the accuracy of detection methods.
4.5 Other Applications
It is used in the synthesis of agrochemicals, such as herbicides and fungicides, to enhance their biological activity and stability. Additionally, it is used in the production of chemical reagents and electronic materials, playing an important role in the fields of chemical analysis and electronic manufacturing.
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