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N3-BENZYL-2-CHLORONICOTINAMIDE
2026-04-14
产品详情
- Cas：65423-28-1
- 产品名称N3-BENZYL-2-CHLORONICOTINAMIDE
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- 简介
- Assay (GC/HPLC): ≥98.0%
- Appearance: Colorless liquid or white crystalline solid
- Melting Point: 34–38 °C
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Single Impurity: ≤0.2%
- Total Impurity: ≤1.0%
Applications
2-Chloro-5-(trifluoromethyl)pyridine is an important fluorinated chloropyridine heterocyclic intermediate. It features high chemical activity and can undergo nucleophilic substitution, Suzuki coupling, Buchwald amination and condensation reactions.
Widely used as molecular building block for antitumor, anti-inflammatory, antibacterial and central nervous system drug intermediates, kinase inhibitors and small-molecule targeted drugs. Also used as key intermediate for agrochemical fungicides, herbicides, organic optoelectronic materials and customized fine chemical synthesis.
Safety Information
Irritating to skin, eyes and respiratory tract. Skin contact may cause redness and irritation; splash into eyes causes stinging and congestion, rinse immediately with plenty of running water. Inhalation of vapor/dust may cause throat discomfort and cough. Ingestion may lead to mild gastrointestinal upset.
Harmful to aquatic organisms; do not discharge directly into water and soil. Operate in fume hood, wear nitrile gloves, safety goggles and protective mask. Keep away from high temperature, open flame and strong oxidants. Store sealed and away from light. Dispose of waste in accordance with hazardous waste regulations.
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