- Assay (HPLC): ≥98.0%
- Appearance: White to off-white crystalline powder
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Single Impurity: ≤0.2%
- Total Impurity: ≤1.0%
Applications
2-Amino-5-bromo-3-methylpyridine is a multi-substituted pyridine heterocyclic intermediate with amino, bromo and methyl functional groups on the pyridine ring. It possesses excellent chemical reactivity and can undergo diazotization, nucleophilic substitution, Suzuki coupling and Buchwald amination reactions. It is widely used as core building block for antitumor, anti-inflammatory, antibacterial and central nervous system pharmaceutical intermediates, as well as kinase inhibitor fragments and targeted small molecule drug synthesis. It is also widely applied in custom fine chemical synthesis, medicinal chemistry structure-activity relationship research and new agrochemical fungicide and herbicide molecular development.
Safety Information
Irritating to skin, eyes and respiratory tract. Inhalation of dust may cause throat itching, dry cough and respiratory mucosal discomfort; direct eye contact will cause obvious stinging, redness and congestion. Avoid inhalation of dust, prolonged skin contact and eye exposure. All operations need to be performed in a fume hood with nitrile gloves, safety goggles and dust mask. Keep away from high temperature, open flame and strong oxidants. Store sealed in dry, dark and ventilated environment. Waste residues and packaging materials shall be disposed strictly in accordance with hazardous chemical regulations to avoid water and soil pollution.
Product
