- Assay (HPLC): ≥98.0%
- Appearance: White to off-white crystalline powder
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Single Impurity: ≤0.2%
- Total Impurity: ≤1.0%
Applications
2-Amino-3-bromopyridine is an important disubstituted pyridine heterocyclic intermediate with active amino and bromo groups on the pyridine ring. It can undergo diazotization, nucleophilic substitution, Suzuki coupling and Buchwald amination reactions efficiently. It is widely used as key building block for antitumor, anti-inflammatory, antibacterial and central nervous system pharmaceutical intermediates, kinase inhibitor fragments and targeted small molecule drug synthesis. It is also commonly used in customized fine chemical synthesis, medicinal chemistry structure optimization and new pesticide fungicide and herbicide molecular research and development.
Safety Information
Irritating to skin, eyes and respiratory tract. Inhalation of dust may cause throat discomfort, dry cough and respiratory mucosal irritation; direct eye contact leads to stinging, redness and conjunctival congestion. Avoid dust inhalation, long-term skin contact and eye exposure. All operations should be carried out in a fume hood with nitrile gloves, safety goggles and dust mask. Keep away from high temperature, open flame and strong oxidants. Store sealed in dry and dark condition. Waste and residual materials must be disposed strictly in accordance with hazardous chemical regulations to prevent water and soil environmental pollution.
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