- Assay (HPLC): ≥98.0%
- Appearance: White to off-white crystalline powder
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Single Impurity: ≤0.2%
- Total Impurity: ≤1.0%
Applications
3-Amino-6-bromopyridazine is an important disubstituted pyridazine heterocyclic intermediate. The bromine atom at 6-position has high activity, easily undergoing nucleophilic substitution, Suzuki coupling, Buchwald amination and condensation reactions. It is widely used as core building block for antitumor, antiviral, antibacterial and central nervous system pharmaceutical intermediates, kinase inhibitors and targeted small molecule drugs. Also applied in medicinal chemistry structure-activity relationship research, custom organic synthesis and pesticide intermediate development.
Safety Information
Irritating to skin, eyes and respiratory tract. Avoid dust inhalation, prolonged skin contact and direct eye exposure. All operations should be performed in a fume hood with nitrile gloves, safety goggles and dust mask. Keep away from high temperature, open flame and strong oxidants. Store sealed in dry, dark and ventilated conditions. Waste residues shall be disposed strictly in accordance with hazardous chemical regulations.
Product
