- Assay (HPLC): ≥98.0%
- Appearance: White to off-white crystalline powder
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Single Impurity: ≤0.2%
- Total Impurity: ≤1.0%
Applications
2-Amino-5-bromo-3-chloropyridine is a high-value trisubstituted pyridine heterocyclic intermediate, containing amino, bromo and chloro functional groups. Multiple active sites enable nucleophilic substitution, Suzuki coupling, Buchwald amination and multi-step derivatization reactions. It is widely used as core building block for antitumor, anti-inflammatory, central nervous system pharmaceutical intermediates and targeted small molecule drugs, also applied in medicinal chemistry structure-activity relationship research and custom fine chemical & agrochemical intermediate synthesis.
Safety Information
Irritating to skin, eyes and respiratory tract. Avoid dust inhalation, prolonged skin contact and direct eye exposure. All operations should be carried out in a fume hood with nitrile gloves, safety goggles and dust mask. Keep away from high temperature, open flame and strong oxidants. Store sealed in dry, dark and ventilated environment. Waste residues shall be disposed strictly in accordance with hazardous chemical regulations.
Product
