- Purity (GC): ≥98.0% (industrial grade); ≥99.0% (reagent grade)
- Appearance: Colorless to pale yellow clear liquid, free of visible impurities
- Moisture Content: ≤0.5%
- Free Acid: ≤0.1%
- Refractive Index: 1.517–1.519
- Heavy Metals (as Pb): ≤10 ppm
Applications
3-Fluorobenzaldehyde is a high-value aromatic fluorine-containing intermediate widely used in pharmaceutical, pesticide, organic synthesis and material science fields, serving as a critical building block for complex functional molecules. In the pharmaceutical industry, it is a core precursor for synthesizing a variety of active pharmaceutical ingredients (APIs), including antidepressants, antitumor drugs, anti-inflammatory agents and antifungal medications; the fluorine atom in its structure enhances drug lipophilicity, metabolic stability and target binding affinity, significantly improving drug efficacy and reducing side effects, making it irreplaceable in the R&D of fluorine-containing innovative drugs. In pesticide development, it is used to prepare high-efficiency, low-toxicity and environmentally friendly pesticides such as insecticides, fungicides and herbicides, effectively improving pest control effects while lowering residual risks in crops and soil. Additionally, it is widely applied in organic synthesis for preparing fluorinated aromatic compounds, dye intermediates, perfume additives and liquid crystal materials; it also acts as a standard reference material in chromatographic analysis and organic synthesis research, supporting accurate qualitative and quantitative detection and lab-scale reaction optimization. Its mild reactivity and stable structure make it suitable for large-scale industrial production and small-batch high-purity research use, covering multiple industrial chains from fine chemicals to advanced materials.
Safety Information
Classified as GHS Category 3 flammable liquid and vapor, Category 2 skin irritant, Category 2 serious eye irritant, and Category 3 specific target organ toxicant (single exposure), 3-Fluorobenzaldehyde poses clear hazards requiring strict operational safeguards. It is flammable, with a low flash point, so it must be kept far away from open flames, heat sources, static electricity and any ignition sources to prevent fire or explosion risks. Direct skin contact causes redness, itching, dryness and mild inflammation; prolonged or repeated contact may lead to dermatitis and skin damage. Eye contact triggers severe irritation, including conjunctival congestion, burning pain and blurred vision, and may cause permanent corneal injury without prompt treatment. Inhalation of its vapor irritates the respiratory tract, causing coughing, throat discomfort, chest tightness and dizziness, especially in poorly ventilated spaces, and long-term inhalation may damage the respiratory mucosa. Accidental ingestion leads to nausea, vomiting, abdominal pain and gastrointestinal irritation, and requires immediate medical attention. During handling, all operations must be conducted in a fume hood or well-ventilated area; operators must wear nitrile gloves, safety goggles and anti-static protective clothing, and avoid inhalation, skin contact or accidental ingestion. No eating, drinking or smoking is allowed during operation, and hands and face must be thoroughly cleaned after work. Storage requires sealed, cool and dry containers below 30 °C, separated from strong oxidizers, strong bases and food materials; the storage area must be equipped with fire-fighting equipment and leakage containment measures. Waste materials and contaminated packaging must be disposed of in accordance with hazardous waste regulations, and must not be discharged into water, soil or sewers to avoid environmental pollution.
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