- Purity (HPLC): ≥98.0% (standard grade); ≥99.0% (high purity grade)
- Appearance: Yellow crystalline powder, free of visible impurities
- Moisture Content: ≤5.0% (hydrate)
- Loss on Drying: ≤1.0% (anhydrous basis)
- Heavy Metals: ≤10 ppm
- Residual Solvents: Meet USP/EP standards
Applications
Fisetin (3,3',4',7-tetrahydroxyflavone) is a natural flavonoid compound widely found in fruits, vegetables and Rhus succedanea plants. It serves as a critical intermediate and active ingredient in pharmaceutical, health care and cosmetic industries. In pharmaceuticals, it exhibits potent antioxidant, anti-inflammatory, anti-tumor and neuroprotective activities, used in developing drugs for cancer, Alzheimer's disease and inflammatory disorders. Its unique structure with ortho-dihydroxyl groups on the B-ring enables strong antiviral effects, supporting treatments for viral hepatitis. In health products, it acts as a dietary supplement for anti-aging, immune enhancement and cardiovascular protection. In cosmetics, it functions as a natural antioxidant and brightening agent, reducing skin aging and pigmentation. It is also applied in organic synthesis and as a reference standard for flavonoid analysis.
Safety Information
Fisetin is classified as a low-toxicity irritant (Xi) with specific safety precautions required during handling and storage. It may cause mild skin, eye and respiratory tract irritation upon direct contact or inhalation of dust. Prolonged skin exposure might lead to dryness, redness or allergic reactions; eye contact could result in conjunctival irritation and discomfort, requiring immediate water flushing. Inhalation of large amounts of dust may irritate the respiratory tract, causing cough or throat discomfort. No severe acute toxicity has been reported, but oral ingestion of excessive doses might cause mild gastrointestinal discomfort. Operations should be performed in well-ventilated areas or fume hoods; operators must wear dust masks, chemical-resistant gloves and safety goggles. Store in a cool, dry, sealed place at -20°C, separated from oxidants, alkalis and food. Avoid release into the environment. Dispose of waste in accordance with local hazardous waste regulations.
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