- Purity (GC): ≥99.0%
- Appearance: Colorless clear liquid
- Moisture Content: ≤0.1%
- Residue on Ignition: ≤0.05%
- Single Impurity: ≤0.2%
- Total Impurity: ≤1.0%
Applications
3-Chlorobenzotrifluoride is a vital fluorine-containing aromatic intermediate widely utilized in pharmaceutical synthesis, agrochemical manufacturing, dye chemistry and fine organic synthesis. The molecule possesses both chlorine substituent and trifluoromethyl group, which endow excellent chemical stability, lipophilicity and structural modifiability. It can participate in nucleophilic substitution, coupling reaction, amination and hydrolysis to build complex fluorinated aromatic frameworks. It is extensively used as a raw material for synthesizing herbicides, fungicides and insecticides in pesticide industry, greatly improving drug efficacy and reducing environmental residue. In pharmaceutical field, it acts as a key building block for the preparation of anti-inflammatory drugs, antibacterial agents and central nervous system medicines. Moreover, it is commonly applied in the production of high-performance organic dyes, fluorinated fine chemicals and chemical reagents, and also serves as an essential solvent and intermediate in laboratory synthetic route development and process scale-up research.
Safety Information
This compound is classified as flammable liquid and mild irritant, presenting fire risk and stimulation to skin, eyes and respiratory tract. Its vapor is heavier than air and may spread to distant ignition sources and flash back. Direct skin contact may cause redness, slight irritation and dryness after long exposure. Eye contact will lead to conjunctival hyperemia, burning pain and temporary discomfort, requiring immediate flushing with abundant running water. Inhalation of high concentration vapor may cause dizziness, cough, sore throat and respiratory discomfort. Accidental ingestion may result in nausea, abdominal pain and gastrointestinal irritation. All operations must be carried out in a well-ventilated fume hood; operators shall wear chemical-resistant gloves, safety goggles and protective mask. Store tightly sealed in a cool, dry and fireproof place, far away from open flame, heat source and strong oxidants. Comply with dangerous goods transportation rules. Waste liquid and contaminated packaging must be treated by professional hazardous waste disposal institutions, and shall not be directly discharged into water bodies or soil to prevent ecological pollution.
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