Apelin-36 is an endogenous active polypeptide ligand of APJ G-protein coupled receptor, acting as vital signaling molecule in cardiovascular regulation, metabolic homeostasis and pathophysiological mechanism research. It is extensively applied in basic medical scientific research, including cardiovascular disease mechanism exploration, hypertension, heart failure and vascular remodeling pathway study. It serves as standard reference substance for peptide quantitative detection, receptor affinity assay and signal pathway validation in biochemical laboratories. It also supports pharmacological screening of APJ targeted new drugs, biomarker development and pathological model construction of obesity, diabetes and metabolic syndrome. In translational medicine research, it participates in nerve regulation, inflammation response and organ protection mechanism analysis, providing core theoretical and experimental basis for novel target drug development, clinical diagnosis marker screening and disease early intervention scheme formulation. Long-term basic research also explores its potential in anti-aging, organ ischemia-reperfusion injury protection and circulatory system stability regulation, greatly expanding application scope in life science and clinical translational research fields.

This polypeptide reagent is strictly for laboratory scientific research only, completely prohibited for clinical human injection, oral administration or direct medical application. Inhalation of dry powder may cause respiratory tract irritation, cough and allergic discomfort; long-term repeated skin contact may induce local allergic reactions. It has no acute high toxicity, but improper operation may interfere with cell signal regulation and animal experimental physiological indicators. Operate in clean fume hood, wear disposable gloves, dust-proof mask and eye protection goggles to prevent powder inhalation and mucous membrane contact. Avoid high temperature, humidity and light exposure to prevent peptide degradation and biological activity failure. Store sealed at -20℃ low temperature, separate from proteinase, strong acid, strong alkali and oxidizing substances. In case of accidental eye contact, rinse with plenty of clean water for more than 15 minutes; if skin contact occurs, wash thoroughly with soap and water. Waste polypeptide powder and diluent shall be treated as biological experimental hazardous waste, disinfected uniformly before discharge, strictly prevent random emission to pollute ecological water and soil environment, and comply with laboratory biological safety management specifications throughout storage and disposal process.