Coumarin-3-carboxylic acid is a key synthetic intermediate in organic chemistry and fine chemical industry, widely used for the preparation of coumarin derivatives, fluorescent probes and pharmaceutical raw materials. It acts as an important building block in the synthesis of antibacterial, anti-inflammatory and antioxidant drugs, as well as cardiovascular and neurological pharmaceutical intermediates. In analytical chemistry, it is commonly used as a fluorescent indicator and chelating reagent for metal ion detection due to its excellent fluorescence luminescence characteristics. It is also applied in the synthesis of perfume essence, dye intermediates, polymer additives and organic fluorescent materials, and serves as a standard reference substance for laboratory organic synthesis research and chromatographic analysis.

This chemical may cause mild irritation to human skin, eyes and respiratory tract under direct exposure. Skin contact may lead to slight redness, dryness and itching, especially for sensitive skin groups. Eye contact will cause obvious stinging, tearing and conjunctival hyperemia. Inhalation of fine dust can irritate nasal and throat mucosa and induce cough and throat discomfort. Accidental oral ingestion may result in mild gastrointestinal symptoms including nausea and abdominal distension. During operation, personnel shall wear dust-proof mask, chemical resistant gloves and protective goggles, and maintain sufficient ventilation in the working area. Store in tightly sealed container at cool, dry and dark place, keep away from strong oxidants, strong alkali and heat sources. Waste materials and contaminated packaging should be disposed of strictly according to hazardous chemical regulations, and arbitrary discharge into water system and soil is forbidden to avoid ecological environment pollution.