- Assay (HPLC): ≥99.0%
- Loss on Drying: ≤0.50%
- Residue on Ignition: ≤0.10%
- Heavy Metals (Pb): ≤10 ppm
- Related Substances: ≤0.80%
- Water Content: ≤0.20%
- Bromide Content: ≤0.15%


Main Uses
This compound is a high-value brominated heterocyclic intermediate with rigid fused-ring structure, widely applied in pharmaceutical synthesis, flame retardant materials, and organic synthetic methodology. It serves as a key building block for constructing bromine-containing heterocyclic frameworks, extensively used in the synthesis of anti-cancer, anti-viral, and anti-inflammatory drug intermediates. The four bromine atoms on the ring enable efficient substitution and coupling reactions (e.g., Suzuki, Heck), supporting precise molecular modification in drug R&D. Beyond pharmaceuticals, it acts as a reactive flame retardant intermediate for epoxy resins, plastics, and textiles, enhancing material fire resistance via bromine radical scavenging. It is also used in synthesizing chiral ligands, organic optoelectronic materials, and as a reference standard in analytical chemistry for brominated compound detection.
Safety Information
This substance is a brominated aromatic compound with moderate irritant and sensitization risks. Direct skin contact may cause redness, itching, and allergic dermatitis, especially in sensitive individuals; prolonged contact should be strictly avoided. Eye contact leads to severe stinging, tearing, and conjunctival congestion, requiring immediate irrigation with copious water for 15+ minutes. Inhalation of dust irritates the respiratory tract, causing cough, throat pain, and shortness of breath; high concentrations may induce bronchitis. Ingestion causes nausea, vomiting, abdominal pain, and diarrhea; large doses may damage the liver and kidneys. Operators must wear chemical-resistant gloves, safety goggles, and dust respirators, and work in a fume hood. Store in sealed, dry, cool, dark places, away from strong alkalis, oxidants, and heat sources. Waste and contaminated packaging must be disposed of as hazardous waste, avoiding release to water/soil to prevent ecological harm from bromide accumulation.
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