Methyl 4-hydroxybenzoate is a widely used high-efficiency antiseptic and preservative, also known as methylparaben. It possesses excellent antibacterial and antifungal properties, effective against molds, yeasts and Gram-positive bacteria. It is extensively applied in cosmetics, personal care products, food beverages, pharmaceutical preparations and daily chemical products for antisepsis and mildew prevention. In organic synthesis, it acts as an important fine chemical intermediate for the synthesis of various pharmaceutical molecules, pesticide derivatives and aromatic compound raw materials. It can also be used as a chemical reagent, chromatographic reference standard and raw material for synthesizing other parabens preservatives. With low toxicity and good compatibility, it is one of the most mainstream broad-spectrum preservatives in industrial production.

This compound has low toxicity under normal usage and belongs to mild irritant. Direct skin contact may cause slight dryness, redness or allergic reaction in sensitive skin groups. Eye contact will lead to stinging, tearing and conjunctival irritation, requiring immediate flushing with plenty of clean water. Inhalation of fine dust may irritate respiratory mucosa and cause throat discomfort and mild cough. Excessive oral intake may induce temporary gastrointestinal discomfort such as nausea and abdominal distension. During handling, wear chemical-resistant gloves, protective goggles and dust mask, and operate in a well-ventilated place. Store in sealed, dry, cool and dark environment, keep away from strong oxidants, strong alkali and high temperature. Waste materials shall be disposed of in accordance with chemical waste regulations, and random discharge into water and soil is prohibited to avoid environmental impact.