- Assay (HPLC): ≥98.0%
- Loss on Drying: ≤0.5%
- Melting Point: 156–160 °C
- Single Maximum Impurity: ≤0.5%
- Total Impurity: ≤1.0%
- Residue on Ignition: ≤0.1%
- Heavy Metals: ≤10 ppm


Applications
This pyrimidine carboxylate derivative is a crucial nitrogen-containing heterocyclic intermediate widely utilized in pharmaceutical and agrochemical synthesis. It contains amino, ester and methyl functional groups on the pyrimidine ring, enabling nucleophilic substitution, hydrolysis, amidation and cyclization reactions to construct diverse pyrimidine molecular skeletons. It acts as a key building block for the synthesis of antitumor drugs, antibacterial agents, antiviral intermediates and cardiovascular pharmaceuticals. It is also extensively applied in the research and production of high-efficiency pesticides, fungicides and veterinary drug raw materials, as well as customized fine chemical synthesis and organic synthetic methodology development.
Safety Information
This pyrimidine compound has low acute toxicity and mild irritant effects on human skin, eyes and respiratory system. Inhalation of fine crystalline dust may cause sore throat, dry cough and slight respiratory discomfort. Skin contact may trigger local redness, itching and mild inflammatory reactions; prolonged and repeated contact may lead to skin dryness and allergic symptoms among sensitive groups. Eye contact will cause obvious burning pain and conjunctival congestion, requiring immediate continuous rinsing with plenty of clean water for no less than 15 minutes. Accidental ingestion may result in mild gastrointestinal discomfort such as nausea and abdominal distension. All handling operations should be performed in a well-ventilated fume hood with chemical-resistant gloves, safety goggles and dust mask. Keep the container tightly sealed, store in a dry, cool and dark environment, and isolate from strong oxidants and strong alkalis. Waste residues and contaminated packaging must be disposed of in accordance with local hazardous waste regulations to prevent water and soil pollution and potential health hazards.
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