- Purity (HPLC): ≥98.0%
- Moisture: ≤0.3%
- Melting Point: 54–58 °C
- Specific Rotation [α]??/D: -15.0° ~ -18.0° (c=1, MeOH)
- Single Impurity: ≤0.5%
- Total Impurities: ≤1.5%
- Heavy Metals: ≤10 ppm
Applications
This is a chiral pyrrolidine building block with N-Boc protection at the 3-position, widely used in pharmaceutical R&D:
- Synthesis of chiral drugs, CNS agents, and protease inhibitors
- Key intermediate for antiviral and anti-inflammatory drug candidates
- Used in asymmetric synthesis and chiral ligand preparation
- For custom synthesis of pyrrolidine-containing APIs and intermediates
Safety Information
Irritant; low acute toxicity, handle with care.
- Inhalation: Dust may irritate respiratory tract; cause cough or throat discomfort.
- Skin Contact: May cause mild irritation, redness, or itching.
- Eye Contact: May cause irritation, tearing, or redness; rinse with plenty of water for ≥15 min.
- Ingestion: May cause nausea, vomiting, or gastrointestinal discomfort.
- Operation: Wear nitrile gloves, safety goggles, and dust mask; work in ventilated area.
- Storage: Keep away from strong acids, oxidants, and moisture; store at 2–8°C for long term.
- Disposal: Treat as hazardous waste; comply with local regulations.
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