- Appearance: Colorless transparent liquid
- Purity (GC): ≥97.0%
- Boiling Point: 25–30 °C (760 mmHg)
- Moisture: ≤0.2%
- Residue on Evaporation: ≤0.1%
- Heavy Metals (Pb): ≤5 ppm
- Related Substances: ≤2.0% (single impurity)
Applications
CAS 27794-53-2 is a highly reactive fluorinated alkyne building block in organic synthesis and fluorine chemistry. Its strained triple bond and mixed halogen substituents (Cl/F) enable unique addition, cycloaddition, and coupling reactions for constructing fluorinated aromatic compounds, heterocycles, and specialty monomers. It serves as a key intermediate in synthesizing fluorinated pharmaceuticals, agrochemicals, and liquid crystal materials, where fluorine enhances metabolic stability and molecular polarity. In materials science, it is used to prepare fluorinated polymers and conductive films via polymerization. Additionally, it acts as a research tool in alkyne chemistry and click chemistry studies, exploring halogen substitution effects on reaction mechanisms.
Safety Information
Classified as GHS02 (F, Flammable Gas); hazard statements H220 (Extremely Flammable Gas), H280 (Contains gas under pressure; may explode if heated).
- Inhalation: Irritates respiratory tract; may cause dizziness/nausea; use fume hood + gas mask.
- Skin/Eye Contact: Gas may cause mild irritation; wear nitrile gloves + safety goggles.
- Ingestion: Not applicable (gas at room temp).
- Chemical Hazards: Highly reactive; explosive polymerization risk at >50 °C; reacts violently with strong oxidants, metals, and moisture; decomposes to toxic Cl/F fumes when heated.
- Storage: Store in pressurized cylinders at -20 °C; keep away from heat, sparks, and open flames; use pressure relief valves.
- Disposal: Release slowly in fume hood per local regulations; never vent to atmosphere; incinerate in approved facility.
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