- Appearance: White to off-white crystalline powder
- Purity (HPLC): ≥98.0%
- Enantiomeric Purity: ≥99.0%
- Moisture: ≤0.2%
- Residue on Ignition: ≤0.1%
- Heavy Metals: ≤10 ppm
- Related Substances: ≤0.5%
Applications
- Pharmaceutical Intermediate: Key intermediate for synthesizing Aprepitant (NK1 receptor antagonist), used to prevent chemotherapy-induced nausea and vomiting (CINV)。
- Fine Chemicals: Used in the synthesis of complex morpholine derivatives and fluorinated aromatic compounds.
- Research & Development: As a reference standard and impurity marker in pharmaceutical analysis.
Safety Information
GHS Hazard: May cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
- Handling: Wear nitrile gloves, safety goggles, and dust mask; operate in a fume hood.
- Storage: Keep sealed under inert gas (nitrogen/argon) at 2–8 °C; avoid moisture, heat, and strong oxidants.
- Disposal: Dispose of as hazardous waste in accordance with local regulations.
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