- Appearance: Slightly yellow turbid liquid
- Activity: ≥500 U/mg
- Protein Content: 5–10 mg/mL
- pH (5% Solution): 6.0–7.5
- Microbial Contamination: Negative
- Stability: 90% activity after 6 months at 4°C
Application
This enzyme catalyzes the reversible cleavage of (R)-mandelonitrile to benzaldehyde and hydrogen cyanide, a key reaction in cyanohydrin synthesis. It is widely used in asymmetric organic synthesis for producing chiral cyanohydrins, critical intermediates for pharmaceuticals, agrochemicals, and fine chemicals. In biocatalysis, it enables high enantioselectivity (>95% ee) under mild conditions, avoiding harsh chemical reagents. It also serves as a research tool in enzymology and metabolic pathway studies, and is used in food additive and fragrance synthesis.
Safety Information
GHS classification: Xn (Harmful); R42/43 (May cause sensitization by inhalation and skin contact).
- Inhalation: Dust/aerosol may trigger allergic respiratory reactions (cough, wheezing) in sensitive individuals.
- Skin Contact: May cause irritation, redness, or allergic dermatitis; avoid prolonged contact.
- Eye Contact: May cause severe irritation, tearing, or conjunctival inflammation.
- Ingestion: May cause nausea, vomiting, or abdominal discomfort; no acute toxicity data.
- Use in fume hood; wear nitrile gloves, safety goggles, and N95 respirator.
- Avoid inhalation of aerosols; prevent skin/eye contact.
- Skin: Rinse with soap and water for 15 min; seek medical care if irritation persists.
- Eyes: Flush with water for ≥15 min; consult a physician.
- Inhalation: Remove to fresh air; if breathing difficulty, get medical help.
- Ingestion: Rinse mouth; do not induce vomiting; seek medical attention.
- Store at 2–8°C, sealed, away from light and moisture; do not freeze.
- Dispose of waste per local hazardous waste regulations; avoid environmental release.
...
Product
