- Appearance: White crystalline powder
- Purity (HPLC): ≥98.0% (typically ≥98.5%)
- Moisture: ≤0.3%
- Melting Point: 88–90 °C
- Total Impurities: ≤1.0%
Application
This compound is a key pharmaceutical intermediate with a rigid piperidine ring, widely used in:
- Central nervous system (CNS) drug synthesis: Precursor for antidepressants, antipsychotics, and analgesics; its 4-phenyl-4-methylamino piperidine scaffold is critical for modulating neurotransmitter receptors.
- Opioid receptor modulators: Intermediate for developing selective opioid ligands, targeting pain management and addiction treatment.
- Organic synthesis: Building block for complex nitrogen-containing heterocyclic compounds, especially in the preparation of bioactive molecules and pharmaceutical candidates.
Safety Information
GHS Classification: Warning
Hazard Statements: H302 (Harmful if swallowed); H315 (Causes skin irritation); H319 (Causes serious eye irritation); H335 (May cause respiratory irritation)
- Acute toxicity: Oral LD50 (rat) >1500 mg/kg (slightly toxic).
- Skin/eye irritation: Moderate irritant; may cause redness, itching, or conjunctival damage.
- Inhalation: Dust may irritate the respiratory tract, causing cough or discomfort.
- Handling: Use in a fume hood; wear nitrile gloves, chemical goggles, and a dust mask.
- Storage: Keep away from strong acids, oxidants, and food; store in a cool, dry place.
- First aid: Rinse skin with soapy water; flush eyes with water for 15 min; seek medical help if swallowed or inhaled.
...
Product
