- Appearance: White crystalline powder
- Purity (HPLC): ≥98.0% (typically ≥98.5%)
- Moisture: ≤0.3%
- Melting Point: 108–110 °C
- Total Impurities: ≤1.0%
Application
This compound is a custom pharmaceutical intermediate featuring a diaryl-substituted acetamide scaffold. It is primarily used in the synthesis of central nervous system (CNS) modulators, especially as a key precursor for developing selective serotonin reuptake inhibitors (SSRIs) and norepinephrine-dopamine reuptake inhibitors (NDRIs). Its unique 3-chlorophenyl and 2-phenylisopropyl substituents enable high binding affinity to neurotransmitter receptors, making it valuable for research into antidepressants, anxiolytics, and cognitive enhancers. It also serves as a building block in organic synthesis for constructing complex nitrogen-containing heterocyclic molecules in drug discovery programs.
Safety Information
GHS Classification: Warning (predicted)
Hazard Statements: H315 (Causes skin irritation); H319 (Causes serious eye irritation); H335 (May cause respiratory irritation)
- Acute toxicity: Oral LD50 (rat) >2000 mg/kg (slightly toxic, predicted)
- Skin/eye irritation: Moderate irritant; direct contact may cause redness, itching, or conjunctival inflammation
- Inhalation: Dust or powder may irritate the respiratory tract, causing cough or throat discomfort
- Handling: Use in a fume hood; wear nitrile gloves, safety goggles, and a dust mask
- Storage: Keep away from strong acids, oxidants, and food; store in a cool, dry, well-ventilated area
- First aid: Rinse skin with plenty of soapy water; flush eyes with running water for 15 minutes; seek medical attention if swallowed or inhaled
...
Product
