- Appearance: Off-white to pale yellow powder
- Purity (HPLC): ≥98.0%
- Moisture: ≤0.5%
- Residue on Ignition: ≤0.2%
- Single Impurity: ≤0.5%
- Heavy Metals (as Pb): ≤20 ppm
Applications
This is a halogenated pyridinone building block used in pharmaceutical and agrochemical synthesis. The bromo, iodo, and methoxy substituents enable selective cross-coupling reactions (Suzuki, Heck, Sonogashira). It serves as a key intermediate in the synthesis of pyridine-based kinase inhibitors and other heterocyclic drug candidates. Also used in academic research for library synthesis and SAR studies.
Safety Information
GHS Classification: Not fully evaluated; treat as irritant.
Signal Word: Warning (assumed)
- H315: Causes skin irritation
- H319: Causes serious eye irritation
- H335: May cause respiratory irritation
Handling: Wear nitrile gloves, safety goggles, dust mask.
Storage: Keep tightly closed at 2–8°C, away from light and oxidants.
Disposal: Dispose as hazardous waste per local regulations.
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