5-Methoxy-2-(trifluoromethyl)pyridine
2026-04-14
产品详情
- Cas:216766-13-1
- 产品名称5-Methoxy-2-(trifluoromethyl)pyridine
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- 简介
Batch NO.:MTP260605
Assay(HPLC):99.23%
Water Content(KF):0.15%
Residual Organic Solvent:MeOH<200ppm, DCM<500ppm, complying with ICH Q3C limits
Single Unknown Impurity:≤0.21%
Total Related Organic Impurity:≤0.58%
Heavy Metal(Pb,As,Cd):All below 10ppm, meets pharmaceutical intermediate grade requirement


Product Usage
This fluorinated pyridine derivative serves as a core fine chemical intermediate dominantly applied in new drug R&D, agrochemical synthesis and advanced organic chemistry research instead of food or daily additive raw material. In pharmaceutical industry, it is the key building block for constructing selective kinase inhibitors, central nervous system targeted small-molecule drugs and anti-inflammatory APIs; its trifluoromethyl and methoxy substituted pyridine skeleton optimizes target protein binding affinity for novel drug candidate synthesis in pre-clinical lab trials. For agrochemical development, the product participates in synthesizing high-efficiency fungicides and insecticides, modifying pesticide molecular structure to enhance pest killing efficiency and reduce crop phytotoxicity. Analytical chemistry labs adopt high-purity grade as standard reference substance for HPLC qualitative and quantitative calibration of fluoropyridine series derivatives during raw material inspection. Besides, it is widely used in cross-coupling reactions including Suzuki and Buchwald-Hartwig condensation as specialized fluorinated pyridine substrate for academic organic synthesis exploration and customized fine chemical pilot production.
Safety Information
Classified as GHS Warning substance with multiple mucosal and skin irritation hazards, marked with hazard statements H315 for skin irritation, H319 for serious eye irritation and H335 for respiratory tract irritation upon vapor inhalation. Operators shall equip nitrile chemical-resistant gloves, full-face splash-proof safety goggles and solvent-resistant lab coat during transferring, weighing and reaction feeding; local exhaust ventilation is required to avoid vapor accumulation in confined working space. In case of skin contact, wash contaminated skin with plenty of flowing soap water over 15 minutes; for eye splashing, continue continuous water irrigation for minimum 15min and visit ophthalmologist for persistent discomfort. Accidental oral intake triggers stomach upset and nausea; forced vomiting is forbidden and emergency hospital treatment must be arranged promptly. Waste liquid and residual solid containing this compound belong to hazardous fluorine organic waste, which must be delivered to certified professional hazardous waste treatment facilities per local environmental statutes, prohibited from direct drainage or regular garbage discard. Store separately from strong oxidizers and concentrated mineral acids to prevent exothermic chemical reaction and toxic fluoride vapor release during long-term warehouse preservation.
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