Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Product Description
Allopurinol (CAS 315-30-0), a purine analog and a xanthine oxidase inhibitor, has a molecular formula of C?H?N?O and a molecular weight of 136.11 Da. Its IUPAC name is 1H-pyrazolo(3,4-d)pyrimidin-4(2H)-one. It usually appears as a white crystalline powder with a bitter taste, and is primarily used as a pharmaceutical agent. It exerts its therapeutic effect by inhibiting xanthine oxidase, an enzyme involved in uric acid production, thereby reducing uric acid levels in the body. It is widely used in the treatment of gout, hyperuricemia associated with cancer therapy, and recurrent calcium oxalate calculi, and also serves as an important intermediate in pharmaceutical R&D.
1. Physical Properties
White crystalline powder with a bitter taste; melting point >300 °C, boiling point 423.2 °C at 760 mmHg, flash point 129.7 °C; refractive index 1.8500 (estimate); solubility 0.35 g/L in water at 25 °C, soluble in 1M NaOH (50 mg/mL), more soluble in alkaline solutions; stable under normal storage conditions.
2. Chemical Properties
As a purine analog, it has a pyrazolo(3,4-d)pyrimidine core structure; it is a xanthine oxidase inhibitor that can inhibit the conversion of hypoxanthine to xanthine and xanthine to uric acid. It is stable under recommended storage conditions, exhibits weak acidity and alkalinity, and is not easy to decompose under normal conditions. It can undergo relevant chemical reactions in pharmaceutical synthesis and has good compatibility with common pharmaceutical excipients.
3. Storage & Safety Properties
Storage: Store in a sealed container at 20–25 °C (68–77 °F), keep dry and light-proof, avoid moisture and heat to prevent degradation. Safety: May cause hypersensitivity reactions, including skin rashes, exfoliative lesions, and other severe reactions; has slight irritation to skin and eyes; avoid inhalation, ingestion or direct contact with skin and eyes; wear protective gloves and goggles during operation; no flammable or explosive hazards. Transportation: Comply with relevant regulations, use sealed packaging to prevent moisture absorption and contamination, and avoid mixing with incompatible substances.
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