Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Product Description
Heparin sodium (CAS: 9041-08-1), also known as sodium heparin, is a glycosaminoglycan belonging to the mucopolysaccharide family, extracted mainly from porcine intestinal mucosa. It is a mixture of polysaccharide chains with different molecular weights, featuring potent anticoagulant properties. It is widely used in clinical research, diagnostic assay manufacturing, biochemical research and cell culture, and also serves as an important pharmaceutical raw material for treating thrombosis.
Molecular Formula & Structure
Molecular Formula: (C??H??NO??SNa)? (polymer mixture, no fixed single molecular formula)
Physical Properties
- Appearance: White or off-white powder; beige in some grades, highly hygroscopic
- Melting Point: Decomposes before melting, no fixed melting point
- Density: Not determined (N/A)
- Boiling Point: Decomposes at high temperature, no fixed boiling point
- Solubility: Easily soluble in water (50 mg/ml, clear, colorless to faintly yellow); insoluble in organic solvents
- Stability: Stable under normal storage conditions; avoid high temperature, moisture and oxidants; solutions should not be autoclaved
- Optical Property: Specific rotation ≥ +50° (40 mg/ml aqueous solution)
Chemical Properties
- CAS Number: 9041-08-1 (confirmed); MDL Number: MFCD00081689
- Chemical Type: Glycosaminoglycan, anticoagulant, biochemical reagent, pharmaceutical raw material
- Molecular Weight: 15,000–19,000 (weight-average molecular weight)
- Chemical Characteristics: Extensively sulfated polysaccharide, composed of alternating D-glucosamine and hexuronic acid linked by glycosidic bonds; has anticoagulant and anti-inflammatory activities
- Application Type: Clinical anticoagulant (treating venous thrombosis, pulmonary embolism); biochemical reagent; diagnostic assay raw material; cell culture supplement
- Toxicity: Low toxicity; no GHS hazard classification; mild irritation on contact with skin/eyes; avoid ingestion
Synthesis Method
- Raw Materials: Porcine intestinal mucosa (main source); auxiliary reagents for extraction and purification
- Synthesis Route: Extracted from qualified porcine intestinal mucosa, undergoes purification, virus inactivation and other processes to obtain the product; production complies with GMP requirements
Storage & Safety
- Storage: Sealed, cool, dry and ventilated; store at room temperature or below 37°C; avoid moisture, high temperature and oxidants; keep away from fire sources
- Package: Sealed, moisture-proof containers with clear labels; comply with pharmaceutical/biochemical reagent standards
- Safety: Operate in a ventilated environment; wear protective equipment; avoid skin/eye contact; wash thoroughly with water after contact; prohibit autoclaving of solutions
- Hazard: Non-flammable; no obvious hazards; large leakage may cause environmental pollution; avoid mixing with oxidants
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