Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Product Description
1,4-Dibromobutane (CAS: 110-52-1), also known as tetramethylene dibromide, is a colorless to pale yellow transparent liquid. It is a common alkyl halide intermediate with high reactivity, widely used in organic synthesis, pharmaceutical manufacturing (e.g., aminophylline, pentoxyverine), and as a cyclization reagent and special reaction solvent.
Molecular Formula & Structure
Molecular Formula: C?H?Br?; Molecular Weight: ~215.91; IUPAC Name: 1,4-dibromobutane; SMILES: BrCCCCBr; InChIKey: ULTHEAFYOOPTTB-UHFFFAOYSA-N.
Physical & Chemical Properties
- Appearance: Colorless to pale yellow clear liquid, with a mild pungent odor; no visible impurities
- Key Properties: Melting Point ~-20 °C (lit.); Boiling Point ~197-198 °C; Density ~1.808 g/mL (25 °C, lit.); Flash Point >110 °C; Refractive Index ~1.519 (n20/D, lit.); Vapor Pressure ~1.63 hPa (25 °C).
- Chemical Traits: Stable under normal temperature and pressure; insoluble in water (~0.35 g/L, 25 °C), soluble in ethanol, ether, chloroform and acetone; incompatible with strong oxidants and strong alkalis; decomposes when heated to release toxic fumes.
- Toxicity: Harmful if ingested, inhaled or absorbed through skin; causes skin and eye irritation, severe eye damage and potential respiratory irritation; may have suspected genotoxicity; GHS signal word "Danger".
Synthesis & Storage
- Synthesis: Mainly prepared by two methods—tetrahydrofuran method and 1,4-butanediol bromination method; the latter can adopt solid superacid catalysis to avoid equipment corrosion, followed by purification via distillation.
- Storage: Sealed in airtight containers; stored in a cool, dry and well-ventilated place below 30 °C; avoid sunlight, high temperature and moisture; separate from oxidants; recommended to store in a cool and dark place below 15 °C; packed in 250kg iron drums.
- Safety: Operate in a well-ventilated environment or outdoors; wear protective gloves, protective clothing, goggles and face protection; avoid dust or vapor inhalation and skin/eye contact; clean up spills promptly; hazardous transport number UN 2810 6.1/PG 3; dispose in accordance with relevant regulations.
...
Product
