Physical Properties

• Appearance: White crystalline solid, odorless or with slight characteristic odor, uniform particle size, no visible impurities, stable at room temperature.
• Melting Point: 109 °C (lit.), melts smoothly without obvious decomposition during melting.
• Boiling Point: 408.8 °C at 760 mmHg (lit.), decomposes slightly above boiling point.
• Solubility: Slightly soluble in water; soluble in ethanol, chloroform, acetone and other polar organic solvents; easily soluble in benzene, toluene and other aromatic organic solvents.
• Density: 1.2 g/cm3 (20 °C, lit.), bulk density 500-550 kg/m3.
• Optical Activity: Has optical activity, with multiple chiral centers, specific rotation undetermined under normal conditions.
• Refractive Index: n20/D 1.562 (lit.), polarizability undetermined.
• Flash Point: 201 °C (closed cup); vapor pressure undetermined under normal temperature and pressure.

Chemical Properties

• Chemical Category: Benzoyloxyazabicyclooctane derivative, also known as Ethyl benzoylecgonine; it is the ethyl ester of benzoylecgonine, structurally similar to cocaine (methyl ester of benzoylecgonine).
• Stability: Stable under normal temperature and pressure (sealed); stable in cool and dry environment; decomposes under strong acid/alkali or high temperature conditions.
• Acid-Base Property: Neutral; stable in neutral environment, can be hydrolyzed under strong acid/alkali conditions to generate corresponding products.
• Hydrolysis: Stable under normal storage conditions; can be hydrolyzed under strong acid/alkali and high temperature conditions, producing benzoylecgonine and ethanol.
• Photostability: Relatively stable to light; long-term exposure to strong light will not cause obvious decomposition, but may affect crystal form and purity.
• Reactivity: Has pharmacological activity, belongs to serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI); high toxicity, GHS hazard symbol GHS06, signal word Danger; mainly formed by transesterification of cocaine and ethanol in the liver when they coexist in the blood.

Applications

• Scientific research field: Mainly used in pharmacological and toxicological research, especially in the research on the combined use of cocaine and ethanol, and the metabolic mechanism of related substances in the human body.
• Medical detection: Used as a standard substance in clinical detection, for the qualitative and quantitative detection of cocaethylene in human blood and urine samples.
• Pharmaceutical research: Used as an intermediate in pharmaceutical research, for the development and research of related drugs and biological reagents.
• Chemical synthesis: Used as an intermediate in organic synthesis, for the synthesis of other benzoyloxyazabicyclooctane derivatives and related compounds.
• Other fields: Used in forensic identification and toxicology analysis, providing technical support for related case handling and research.

Storage & Handling

• Storage: Sealed, cool, dry and dark; away from sunlight, heat and oxidants; stored in a dedicated storage area, marked with hazard signs, and strictly prohibited from mixed storage with other chemicals.
• Temperature: 2-8 °C for long-term storage; refrigerated storage is mandatory; shelf life 12 months under proper storage conditions; use as soon as possible after opening.
• Packaging: Sealed glass bottle (10g/25g), with anti-leakage and anti-breakage design; marked with product name, CAS number, purity, hazard signs and storage requirements.
• Precautions: Operate in a well-ventilated and professional experimental environment; strictly abide by relevant operating specifications; wear professional protective equipment (protective gloves, goggles, gas mask); avoid inhalation, ingestion and direct skin/eye contact; in case of accidental contact, rinse with plenty of water immediately and seek medical attention; dispose of waste in accordance with national hazardous waste treatment regulations; strictly controlled and managed in accordance with controlled drug management requirements.

Description