Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Physical Properties
- Appearance: Brick-red microcrystals with slight violet luster, odorless, uniform particle size, no visible impurities, stable at room temperature.
- Melting Point: 235 °C (lit.), decomposes during melting without obvious melting process.
- Boiling Point: Undetermined under normal atmospheric pressure, decomposes before boiling.
- Solubility: Slightly soluble in cold water, ethanol and lanolin; soluble in boiling water, acetic acid, glycerol, ethylene glycol and propylene glycol; insoluble in acetone, benzene, chloroform, diethyl ether and toluene; water solubility 15.9 g/L at 25 °C.
- Density: Undetermined (20 °C), bulk density 480-530 kg/m3.
- Optical Activity: No optical activity, no chiral center.
- Refractive Index: Undetermined, log Kow -0.30 (25 °C).
- Flash Point: Undetermined; vapor pressure 3.51×10?11 mmHg at 25 °C.
Chemical Properties
- Chemical Category: Heterocyclic aromatic azo compound, also known as Pyridium (registered trademark); a common urinary tract analgesic drug raw material.
- Stability: Stable under normal temperature and pressure (sealed); stable in cool and dry environment; decomposes under strong acid/alkali or high temperature conditions; reasonably anticipated to be a human carcinogen based on animal experiment evidence.
- Acid-Base Property: Weakly acidic; stable in neutral and weakly acidic environments, not easy to hydrolyze under normal conditions.
- Hydrolysis: Stable under normal storage conditions; can be decomposed under strong acid/alkali and high temperature conditions, producing corresponding aromatic amine derivatives.
- Photostability: Relatively stable to light; long-term exposure to strong light may cause slight discoloration, but does not affect product performance.
- Reactivity: Has obvious analgesic activity, used to relieve pain, burning and discomfort caused by urinary tract infection or irritation; has certain toxicity, GHS hazard symbols Xn, C; can form complexes with metal ions.
Applications
- Pharmaceutical industry: Used as a urinary tract analgesic drug raw material, used to relieve pain, burning and discomfort associated with urinary tract infections or irritation; often used in combination with sulfonamides and antibiotics.
- Medical detection: Used as a standard substance in clinical detection, for the qualitative and quantitative detection of phenazopyridine hydrochloride in human blood and urine samples.
- Scientific research field: Mainly used in pharmacological, toxicological and carcinogenicity research, especially in the research on the mechanism of action of urinary tract analgesics and related carcinogenicity studies.
- Chemical synthesis: Used as an intermediate in organic synthesis, for the synthesis of other heterocyclic azo compounds and related pharmaceutical derivatives.
- Other fields: Used in forensic identification and pharmaceutical quality control, providing technical support for related drug detection and research.
Storage & Handling
- Storage: Sealed, cool, dry and dark; away from sunlight, heat and oxidants; stored in a dedicated storage area, marked with hazard signs, and strictly prohibited from mixed storage with food, feed and other chemicals.
- Temperature: 2-8 °C for long-term storage (preferred), or 20-25 °C with excursions permitted to 15-30 °C; -20 °C freezer storage is recommended for small batches; shelf life 12 months under proper storage conditions; use as soon as possible after opening.
- Packaging: Sealed amber vial or glass bottle (10g/25g), with anti-leakage and anti-breakage design; marked with product name, CAS number, purity, hazard signs and storage requirements; stored in amber vial to avoid light exposure.
- Precautions: Operate in a well-ventilated and professional experimental environment; strictly abide by relevant operating specifications; wear professional protective equipment (protective gloves, goggles, mask); avoid inhalation, ingestion and direct skin/eye contact; in case of accidental contact, rinse with plenty of water immediately and seek medical attention; dispose of waste in accordance with national hazardous waste treatment regulations; stored away from open fire and high-temperature sources, classified as flammable liquid storage category 10.
Description
Phenazopyridine hydrochloride (CAS: 136-40-3) is a heterocyclic aromatic azo compound with the molecular formula C??H??ClN? and average molecular weight 249.7. It is brick-red microcrystals with slight violet luster (purity ≥98.0% HPLC), odorless. It is a common urinary tract analgesic drug raw material, which can relieve pain and discomfort caused by urinary tract infection or irritation. It is reasonably anticipated to be a human carcinogen based on animal experiment evidence, with certain toxicity. It is widely used in pharmaceutical, medical detection and scientific research fields. It needs to be stored in a sealed, cool and dark environment, and strictly managed in accordance with relevant regulations to ensure storage and operation safety.
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