Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Product Description
N-[p-(dihydroxystibino)phenyl]acetamide Sb-oxide, monosodium salt (CAS: 138-31-8) is an organic antimony compound with a unique structure containing acetamide and stibino functional groups. It appears as a white crystalline solid, odorless, and has specific solubility characteristics. It possesses anti-fungal and anti-bacterial properties, making it widely used in the pharmaceutical industry and plays a key role in the treatment of various infections.
Uses
Pharmaceutical: As an important pharmaceutical intermediate and active ingredient, it is mainly used in the field of anti-infection, with significant anti-fungal and anti-bacterial activities. It is involved in the treatment of various infectious diseases and is a key raw material for the development of related anti-infection drugs.
Chemical Research & Development: Serves as an analytical standard in chemical and pharmaceutical research, and a model compound for studying the chemical properties and reaction mechanisms of organic antimony compounds. It is also used in the research and development of new organic antimony derivatives.
Other Uses: Due to its unique chemical structure and properties, it can be used in the research of specialty chemicals related to antimony compounds, providing support for the development of new materials and chemical products.
Molecular Formula & Structure
- Molecular Formula: C?H?NNaO?Sb
- Molecular Weight: 308.87 g/mol
- IUPAC Name: N-[4-(dihydroxystibino)phenyl]acetamide antimony oxide monosodium salt
- Synonyms: Sodium p-acetylaminophenylantimonate; p-Acetamidobenzenestibonic acid sodium salt; Stibacetin; Stibenyl;
- EINECS Number: 205-323-2
- Chemical Structure: A complex organic antimony compound, containing a phenyl group substituted with acetamide and dihydroxystibino groups, and a sodium ion as the counterion. Its structure is the basis for its anti-fungal, anti-bacterial and other biological activities.
Physical & Chemical Properties
- Appearance: White crystalline solid, odorless, no visible impurities.
- Melting Point: 240–248 °C (decomp).
- Specific Rotation: +12° (c = 0.5 in water, 25 °C).
- Solubility: Has specific solubility characteristics, soluble in water (10–15 mg/mL at 25 °C) and methanol, slightly soluble in ethanol, and has limited solubility in non-polar solvents such as hexane.
- Boiling Point: 480.5±45.0 °C (predicted); Density: 1.82±0.1 g/cm3 (predicted).
- Stability: Stable under normal conditions; may decompose when heated to high temperatures (above 240 °C), emitting toxic fumes; incompatible with strong oxidants; avoid light and moisture.
- Toxicity: Toxic by intraperitoneal route (LD??, mouse: 150 mg/kg); may cause irritation to the skin, eyes and respiratory tract; avoid direct contact and inhalation.
Synthesis & Storage
- Synthesis: Prepared by chemical synthesis methods, through the reaction of appropriate raw materials, followed by purification steps to obtain high-purity products, which are widely used in industrial production.
- Storage: Sealed in airtight containers; stored under inert atmosphere at -20 °C (long-term); avoid light, moisture, high temperature and strong oxidants; shelf life is 2 years under proper storage conditions.
- Safety: Operate in a well-ventilated environment; wear professional protective gear (mask, gloves, goggles) to avoid inhalation, skin and eye contact; do not eat, drink or smoke during operation; rinse with plenty of water if contact occurs; dispose of waste in accordance with hazardous chemical regulations.
...
Product
