Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Product Description
Galantamine Hydrobromide is a tertiary amine alkaloid (extracted or artificially synthesized), white to off-white odorless crystalline powder. As a key pharmaceutical API, it is used for mild to moderate Alzheimer's disease treatment, reversing non-depolarizing neuromuscular blocker-induced muscle relaxation, and as a neuroscience research reagent.
Uses
Pharmaceutical API: Treats mild to moderate Alzheimer's disease; reverses muscle relaxation during surgical anesthesia caused by non-depolarizing neuromuscular blockers.
Laboratory Research: Tool compound for neuroscience and neurodegenerative disease research; pharmaceutical quality control reference standard.
Molecular Formula & Structure
- Molecular Formula: C??H??NO?·HBr
- Molecular Weight: 368.27 g/mol
- IUPAC Name: (4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol monohydrobromide
- Chemical Structure: Tertiary amine alkaloid with benzofuro[3a,3,2-ef][2]benzazepine core, forming hydrobromide salt for better solubility and stability.
Physical & Chemical Properties
- Appearance: White to off-white crystalline powder, odorless, no visible impurities.
- Density: 1.30 ± 0.1 g/cm3 (predicted); Melting Point: 254–258 °C (decomposes).
- Solubility: Sparingly soluble in water; slightly soluble in anhydrous ethanol; soluble in dilute alkali and methanol.
- Boiling Point: 439.7 ± 45.0 °C (predicted); Flash Point: 219.7 °C.
- Stability: Stable under normal conditions; incompatible with strong oxidants/acids; light/moisture sensitive.
- Toxicity: Toxic if swallowed; may cause skin/eye irritation; Hazard Code: T; UN Number: UN 2811 (6.1/PG 3).
Synthesis & Storage
- Synthesis: Natural extraction and artificial synthesis (total/semi-synthesis); semi-synthesis is main industrial method.
- Storage: Sealed, light-proof; long-term at -20 °C (inert atmosphere); short-term at 2–8 °C; shelf life 2–3 years.
- Safety: Operate in well-ventilated area; wear protective gear; avoid contact with skin/eyes; keep away from children.
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