Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
- Product Name: Glabridin
- CAS Number: 59870-68-7
- Molecular Formula: C??H??O?
- Molecular Weight: 324.37 g/mol
- Synonyms: 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[6,5-f]chromen-3-yl]benzene-1,3-diol; Licorice Flavone
- Classification: Natural flavonoid, cosmetic whitening agent, anti-inflammatory agent, antioxidant, pharmaceutical intermediate
Physical & Chemical Properties
- Appearance: White to light brown crystalline powder; high-purity (≥98%) product is white, low-purity product is yellowish-brown; odorless, no visible impurities, uniform powder state.
- Melting Point: 154-158°C; stable melting range, no decomposition during melting.
- Boiling Point: 518.6±50.0°C (Predicted); no obvious decomposition at high temperature.
- Density: 1.257±0.06 g/cm3 (Predicted); stable under normal temperature and pressure.
- Refractive Index: 1.610 (Predicted); consistent with the characteristics of flavonoid compounds.
- Flash Point: 267.4±30.1°C; non-flammable under conventional use conditions.
- Solubility: Insoluble in water; easily soluble in organic solvents such as ethanol, propylene glycol, 1,3-butanediol, DMSO; slightly soluble in vegetable oils.
- Stability: Hygroscopic; sensitive to strong light and high temperature; stable under sealed and low-temperature conditions; avoid long-term exposure to air, light and high temperature to prevent oxidation and discoloration.
- Key Parameters: Purity ≥98.0% (HPLC); Loss on Drying ≤5.0%; Heavy Metals ≤10 ppm; Residue on Ignition ≤0.5%.
Uses
Glabridin (CAS 59870-68-7) is a rare isoflavanoid extracted from the roots of Glycyrrhiza glabra L., with high safety and multiple biological activities, widely used in cosmetics, medicine, food and other fields. In cosmetics, it acts as a core whitening and brightening agent, inhibiting melanin production and tyrosinase activity, reducing pigmentation and freckles; it also has anti-inflammatory, antibacterial and antioxidant effects, soothing sensitive skin, improving redness and acne, and enhancing skin elasticity and anti-aging ability, often added to creams, essences, masks and lotions. In medicine, it is used as an auxiliary raw material for anti-inflammatory, antibacterial, antioxidant and anti-tumor drugs, helping to treat skin inflammation, acne, cardiovascular diseases and osteoporosis, and has a protective effect on nerves and liver. In the food industry, it serves as a natural antioxidant and preservative, extending the shelf life of food and improving food safety. In addition, it can be used as a research reagent for studying PPARγ activation, fatty acid oxidation and other biological processes.
Packaging & Storage
Packaging: Laboratory grade: 10g, 50g, 100g sealed brown glass bottles to prevent light, moisture and oxidation; industrial grade: 1kg, 5kg, 25kg aluminum foil bags or HDPE drums with inner PE liners, labeled with product name, CAS number, batch number, manufacturing date, expiry date, purity and storage precautions. Storage: Store in a cool, dry, dark and well-ventilated warehouse at 2-8°C; keep tightly sealed to prevent moisture absorption, oxidation and contamination; avoid strong light, high temperature and humid environment; do not mix with toxic, harmful and oxidizing substances. Shelf life: 24 months under recommended sealed storage conditions; use as soon as possible after opening to avoid deterioration. Transportation: Avoid transportation under high temperature, strong light and rain; use ice packs for low-temperature transportation in summer; prevent collision and damage to packaging; do not transport together with incompatible substances. Handling: Operate in a well-ventilated area; avoid inhalation of powder and contact with skin, eyes and mucous membranes; wear dust-proof gloves, goggles and protective clothing during operation; wash skin thoroughly with soap and water after contact; if splashed into eyes, rinse with plenty of flowing water for 10-15 minutes and seek medical help in time.
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