Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
CAS Number: 179688-29-0
Molecular Formula: C??H??N?O?
Molecular Weight: 280.27 g/mol
Synonyms: 6,7-Di(2-methoxyethoxy)-3H-quinazolin-4-one; Quinazolinone derivative intermediate
Classification: Quinazolinone heterocyclic compound, pharmaceutical intermediate, kinase inhibitor intermediate, fine chemical raw material
Physical & Chemical Properties
Appearance: White to off-white crystalline powder, odorless
Melting Point: 186–190 °C
Boiling Point: Decomposes at high temperature, no fixed boiling point
Density: 1.26±0.05 g/cm3
Solubility: Slightly soluble in water; soluble in methanol, ethanol, DMSO, DMF and acetone; insoluble in alkane solvents
Stability: Stable under normal temperature and sealed dry condition; light-sensitive and heat-sensitive; avoid strong oxidants, high temperature and prolonged heating; stable under neutral and weak acidic conditions
Key Parameters: Purity ≥98.0% (HPLC); Loss on Drying ≤0.5%; Residue on Ignition ≤0.1%
Uses
This product is a key quinazolinone heterocyclic intermediate.
Mainly used as pharmaceutical raw material and organic synthesis building block for the preparation of antitumor drugs, tyrosine kinase inhibitors and targeted therapeutic drug intermediates.
Widely applied in the research and development of quinazoline derivative APIs, biochemical pharmacological research and custom organic synthesis.
Also used in fine chemical synthesis, heterocyclic derivative preparation and laboratory chemical research reagents.
Packaging & Storage
Packaging
Laboratory grade: 1g, 5g, 10g sealed brown glass bottles
Industrial grade: 25g, 100g, 1kg aluminum foil vacuum bag with moisture-proof packaging
Storage: Store in cool, dry, dark and well-ventilated place; keep tightly sealed, strictly moisture-proof and light-proof; away from high temperature and strong oxidants
Shelf Life: 24 months under sealed, dry and dark storage
Transportation: Avoid rain, humidity and strong light; handle gently to prevent package damage and moisture absorption
Comprehensive Specification Table

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