Lapatinib ditosylate-Shandong Huashang Chemical Co., Ltd.

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Lapatinib ditosylate

2026-04-14

产品详情

Cas：388082-78-8
产品名称Lapatinib ditosylate 查看相似产品 >

简介

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: Lapatinib ditosylate

Alias: Lapatinib Ditosylate Monohydrate; N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate); Lapatinib tosylate; GW-572016; Tykerb; MFCD09264195; UNII-4WK72K94MC; Lapatinib Ditosilate

CAS No.: 388082-78-8

EINECS No.: 642-915-3

Molecular Formula: C??H??ClFN?O??S?

Molecular Weight: 943.48 g/mol

Classification: Quinazoline derivative, tyrosine kinase inhibitor, pharmaceutical raw material (API), anti-tumor drug, small molecule inhibitor

Physical & Chemical Properties

Appearance: Colorless to pale yellow crystalline solid or yellow powder, odorless; stable under normal conditions, incompatible with strong oxidizing agents and strong acids; light and high-temperature sensitive

Density: 1.403 g/mL (20.84℃); refractive index n??/D 1.5520 (lit.); LogP: 12.26-12.33; PSA: 240.23-249.46

Melting Point: 237-239℃ (dec.)

Boiling Point: 750.7℃ (760 mmHg); decomposes at high temperature

Solubility: Slightly soluble in water (0.007 mg/mL, 25℃) and 0.1N HCl (0.001 mg/mL, 25℃); freely soluble in DMSO, methanol and ethanol; slightly soluble in chloroform

Flash Point: 407.8℃; Vapor Pressure: negligible (25℃); precise mass: 942.1841

Purity: ≥95.0% (industrial); ≥98.0% (HPLC, analytical); ≥99.0% (pharmaceutical, API); meets USP/EP standards

Storage Condition: Sealed, 2-8℃ cool and dry place, protected from light and moisture; avoid high temperature, light and strong oxidizing agents; store in inert atmosphere; avoid contact and inhalation

Main Uses

Pharmaceutical Field: Oral small-molecule tyrosine kinase inhibitor, inhibits EGFR (IC50=10.2 nM) and ErbB-2 (IC50=9.8 nM); combined with capecitabine for advanced/metastatic ErbB-2 overexpressed breast cancer; potential for head and neck cancer, bladder cancer treatment
Medical Research Field: Research reagent for oncology and pharmacology studies; used in tumor models, drug resistance mechanism research, combined therapy development; analytical standard for drug quality control and pharmacokinetics

Specification Table

Item	Specification	Unit	Remarks
Product Name	Lapatinib ditosylate	—	Alias: Tykerb, GW-572016
CAS Number	388082-78-8	—
Molecular Formula	C??H??ClFN?O??S?	—
Molecular Weight	943.48	g/mol
Appearance	Colorless to pale yellow crystalline solid or yellow powder	—	Odorless; light and high-temperature sensitive
Melting Point	237-239	℃	dec. = decomposes
Purity	≥99.0	%	Pharmaceutical/API grade; HPLC

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联系我们

Shandong Huashang Chemical Co., Ltd.

联系人 Maisey Wang
联系手机+8619031118161
联系电话+8619031-118161-+8616768688388
所在地址No. 57 Industrial South Road,Shandong Province,china

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