Prostaglandin E1-Shandong Huashang Chemical Co., Ltd.

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Prostaglandin E1

2026-04-14

产品详情

Cas：745-65-3
产品名称Prostaglandin E1 查看相似产品 >

简介

Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: Prostaglandin E1

Alias: PGE1; Prostaglandin E1; Alprostadil; (1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentaneheptanoic acid; 11α,15(S)-Dihydroxy-9-oxoprost-13-en-1-oic acid; MFCD00005847; UNII-0K3Q163J6K; RTECS UE2450000; PubChem: 5280468; ChEMBL: ChEMBL1541

CAS No.: 745-65-3

EINECS No.: 212-010-6

Molecular Formula: C??H??O?

Molecular Weight: 354.48 g/mol

Classification: Organic compound, prostaglandin, bioactive molecule, pharmaceutical API, vasodilator, antiplatelet agent, fine chemical, research reagent

Physical & Chemical Properties

Appearance: White to off-white crystalline powder, odorless; unstable under light and high temperature, easily oxidized; incompatible with strong oxidizing agents and strong bases; slightly hygroscopic; may cause mild irritation upon contact with skin and eyes.

Density: 1.149 g/cm3 (25℃, predicted); refractive index n??/D 1.520 (predicted); LogP: 3.24 (predicted); PSA: 94.83; precise mass: 354.2406; optical rotation (α)??/D -60° to -70° (c=1, ethanol).

Melting Point: 115-118℃ (lit.); decomposes at higher temperatures, especially in the presence of light and oxygen.

Boiling Point: 582.1±50.0℃ (predicted, atmospheric pressure); decomposes before boiling if not protected from light.

Solubility: Slightly soluble in water (0.1 g/100mL at 25℃); soluble in ethanol, methanol, acetone, DMSO and ethyl acetate; insoluble in non-polar solvents such as benzene and chloroform; solubility increases in alkaline solutions.

Flash Point: 305.8±30.1℃ (predicted); Vapor Pressure: 0.0±3.7 mmHg (25℃, predicted); pKa: 4.8 (25℃).

Purity: ≥98.0% (analytical grade, HPLC); ≥99.0% (pharmaceutical grade, USP/BP); ≥99.5% (high-purity grade, for research use).

Storage Condition: Sealed, stored in a cool and dry place at -20℃, protected from light, moisture and oxygen; keep container tightly closed; avoid high temperature, open flame and contact with oxidizing agents and strong bases; store in an inert atmosphere (nitrogen or argon); avoid repeated freeze-thaw cycles.

Main Uses

Pharmaceutical & API Field: As a key API, it is used clinically as a vasodilator, antiplatelet agent and smooth muscle relaxant; used in the treatment of erectile dysfunction, peripheral arterial disease, pulmonary hypertension and neonatal patent ductus arteriosus (PDA).
Research & Laboratory Field: Used as a research reagent in molecular biology, pharmacology and biochemistry; used to study prostaglandin signaling pathways, cell proliferation, inflammation and vascular physiology; used as a reference substance for drug analysis and detection.
Biomedical Field: Applied in cell culture as a growth factor to promote cell proliferation and differentiation; used in the research of tissue engineering and regenerative medicine.
Other Fields: Used in the development and detection of pharmaceutical quality standards; applied in preclinical research of cardiovascular diseases, inflammatory disorders and reproductive system diseases.

Specification Table

Item	Specification	Unit	Remarks
Product Name	Prostaglandin E1	—	Alias: PGE1, Alprostadil
CAS Number	745-65-3	—	TSCA listed; light-sensitive and oxidizable
Molecular Formula	C??H??O?	—	Linear formula: (1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentaneheptanoic acid
Molecular Weight	354.48	g/mol
Appearance	White to off-white crystalline powder	—	Odorless; slightly hygroscopic; light-sensitive
Melting Point	115-118	℃	lit. = literature value; decomposes at high temperature
Purity	≥99.0	%	Pharmaceutical grade; USP/BP standard

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联系我们

Shandong Huashang Chemical Co., Ltd.

联系人 Maisey Wang
联系手机+8619031118161
联系电话+8619031-118161-+8616768688388
所在地址No. 57 Industrial South Road,Shandong Province,china

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