Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: (Trifluoromethyl)trimethylsilane
Alias: Trimethyl(trifluoromethyl)silane; TMSCF3; Ruppert-Prakash reagent
CAS No. : 81290-20-2
EINECS No. : Not available
Molecular Formula: C4H9F3Si
Molecular Weight: 142.00 g/mol
Classification: Fluorinated silane reagent; Trifluoromethylating agent; Organic synthesis intermediate
Physical & Chemical Properties
Appearance: Colorless transparent volatile liquid
Odor: Characteristic ether-like odor
Solubility: Soluble in ether, dichloromethane, toluene and common organic solvents; insoluble in water
Stability: Sensitive to moisture; flammable; store sealed under inert gas, low temperature away from fire and oxidants
Specification Table
| Item | Specification | Unit | Remarks |
| Product Name | (Trifluoromethyl)trimethylsilane | — | TMSCF3 |
| CAS Number | 81290-20-2 | — | Trifluoromethylation reagent |
| Appearance | Colorless transparent volatile liquid | — | Low boiling point |
| Molecular Formula | C4H9F3Si | — | Fluorosilane compound |
| Molecular Weight | 142.00 | g/mol | — |
| Purity | ≥98.0 | % | GC grade |
Main Uses
- Classic trifluoromethylation reagent for introducing CF3 group in organic synthesis
- Widely used in pharmaceutical, pesticide and fluorine-containing fine chemical synthesis
- Used for preparation of trifluoromethylated aromatic compounds, heterocyclic compounds
- Important building block in fluorine chemistry and medical intermediate synthesis
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