Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.
Basic Information
Product Name: Bivalirudin
Alias: Bivalirudin trifluoroacetate; Hirulog; BG-8967
CAS No. : 128270-60-0
Molecular Formula: C98H138N24O33
Molecular Weight: 2180.29 g/mol
Classification: Peptide API; Anticoagulant; Direct thrombin inhibitor (DTI)
Physical & Chemical Properties
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Solubility: Soluble in water (≥43.5 mg/mL), DMSO; slightly soluble in ethanol
- Stability: Light sensitive; hygroscopic; store at -20°C (dry and sealed)
- Sequence: D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
Specification Table
| Item | Specification | Unit | Remarks |
| Product Name | Bivalirudin | — | Peptide API |
| CAS No. | 128270-60-0 | — | Pharma grade |
| Appearance | White to off-white powder | — | Lyophilized powder |
| Molecular Formula | C98H138N24O33 | — | 20 amino acid peptide |
| Molecular Weight | 2180.29 | g/mol | Anhydrous free base |
| Purity | ≥98.0 | % | HPLC |
| Single Impurity | ≤1.0 | % | HPLC |
| Water Content | ≤10.0 | % | Karl Fischer |
Main Uses
- Anticoagulant for PCI: Direct thrombin inhibitor for percutaneous coronary intervention (PCI) and unstable angina PTCA.
- HIT/HITTS: Anticoagulation in patients with heparin-induced thrombocytopenia (HIT) or HITTS undergoing PCI.
- Pharmaceutical API: Active ingredient in injectable anticoagulant formulations (brand: Angiomax/Angiox).
- Research: Used in thrombosis research and as a biochemical reagent for thrombin inhibition studies.
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