Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise specializing in the research and development, manufacturing, and sales of fine chemicals. Headquartered in Jinan, Shandong, China, we are committed to delivering high-quality products to our global partners. Currently, over 90% of our products are exported to developed markets, including North America, Europe, Japan, South Korea, and the Middle East.

Basic Information

Product Name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

Alias: 5,6,7,8-Tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine hydrochloride; Triazolopyrazine hydrochloride

CAS No. : 762240-92-6

Molecular Formula: C6H8ClF3N4

Molecular Weight: 228.60 g/mol

Classification: Heterocyclic intermediate; Fluorinated triazolopyrazine; Pharmaceutical API intermediate

Physical & Chemical Properties

• Appearance: White crystalline powder
• Odor: Odorless
• Melting Point: 236–246 °C
• Solubility: Soluble in water, methanol, DMSO (100 mg/mL); slightly soluble in ethanol
• Stability: Stable under dry, room temperature; hygroscopic; avoid strong base and high temperature
• Boiling Point: 266.2 ± 50.0 °C (760 mmHg)
• Flash Point: 114.8 ± 30.1 °C

Specification Table

Main Uses

1. Pharmaceutical Intermediate: Key building block for synthesizing triazolopyrazine-based drugs, especially CNS, anti-inflammatory, and antiviral agents.
2. Fluorinated Heterocyclic Chemistry: Used in the synthesis of complex molecules with trifluoromethyl and triazole moieties for drug discovery.
3. Research Reagent: Employed in biochemical research as a reference compound and synthetic intermediate for target validation.