Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Genistein
CAS Number: 446-72-0
Alias: 4',5,7-Trihydroxyisoflavone, Prunetol
Molecular Formula: C15H10O5
Molecular Weight: 270.24 g/mol
Structural Information
- Structure Type: Natural isoflavonoid compound, a typical member of isoflavone family.
- Structural Features: Contains three phenolic hydroxyl groups on the isoflavone skeleton with complete conjugated aromatic system. The special molecular structure endows it with good biological activity, antioxidant capacity and polar characteristics.
Physical & Chemical Properties
- Appearance: Off-white to pale yellow crystalline powder
- Odor: Odorless
- Melting Point: 297 - 299 °C (decomposition)
- Solubility: Slightly soluble in cold water, soluble in hot water, ethanol, methanol, acetone and dilute alkaline solution; insoluble in ether, chloroform, benzene and petroleum ether
- Stability: Stable under dry, cool and dark conditions. Easy to be oxidized and discolored under long-term exposure to strong light, high temperature or air. Avoid contact with strong oxidants.
Synthesis & Applications
Synthesis Method
Mainly extracted and purified from natural plants such as soybean, red clover and kudzu root. It can also be produced by chemical synthesis. Taking aromatic compounds as raw materials, the finished product is obtained through cyclization, hydroxylation reaction, recrystallization and purification process.
Main Applications
- Pharmaceutical industry: Important pharmaceutical intermediate. It has estrogen-like activity, antioxidant, anti-tumor, anti-inflammatory and lipid-regulating effects, widely used in pharmaceutical research and development.
- Health care products: Common raw material for dietary supplements, applied for regulating endocrine, protecting bones and anti-oxidation.
- Food industry: Used as natural food antioxidant and nutritional fortifier.
- Cosmetics: Added into skin care products to resist free radicals, improve skin condition and delay aging.
Safety & Storage Instructions
- Hazard Classification: Low toxicity, no obvious irritation to skin and mucous membranes under normal use.
- Personal Protection: Wear dust mask and chemical resistant gloves during operation. Avoid inhalation of dust and direct contact with eyes.
- Storage Condition: Keep containers tightly sealed. Store in cool, dry, dark and well-ventilated environment at room temperature. Keep away from heat sources, direct sunlight and oxidizing substances.
- Transportation: Classified as general chemical goods, no special dangerous goods transport regulations. Prevent package damage, moisture and light exposure during transportation.
Quality & Spectral Data
- Purity (HPLC): ≥98.0% / ≥99.0%
- Loss on Drying: ≤1.0%
- Residue on Ignition: ≤0.2%
- Heavy Metals: ≤10 ppm
- 1H NMR Spectrum: Consistent with standard reference spectrum
- IR Spectrum: Characteristic absorption peaks match the standard structure
Information Summary Table
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