Basic Information
- CAS Number: 52190-28-0
- Molecular Formula: C??H?BrO?
- Molecular Weight: 257.08 g/mol
- Synonyms: 1-(1,3-Benzodioxol-5-yl)-2-bromopropan-1-one; 2-Bromo-3',4'-(methylenedioxy)propiophenone; Bromo-3',4'-(methylenedioxy)propiophenone; 1-(Benzo[d][1,3]dioxol-5-yl)-2-bromo-1-propanone
- Classification: Organic raw material, ketone compound, pharmaceutical intermediate, fine chemical raw material, organic synthesis intermediate
- Customs Code: 2932999099
Physical & Chemical Properties
- Appearance: Brown crystalline powder; slight characteristic odor; slightly hygroscopic; stable under proper storage conditions, no obvious color change under normal temperature and pressure.
- Melting Point: 89.89°C; stable before melting, no decomposition at melting point range, melts into light brown liquid.
- Boiling Point: 345.7±42.0°C (760 mmHg, predicted); 313.84°C (calculated); stable under normal pressure, no obvious decomposition during boiling process.
- Solubility: 5364 mg/L (25°C, water); soluble in water at room temperature, forming a light brown clear solution; soluble in methanol, ethanol, acetone and other polar organic solvents; slightly soluble in ether, toluene and other non-polar solvents.
- Stability: Stable under ambient conditions; incompatible with strong acids, strong bases and oxidizing agents; avoid excessive heat, direct sunlight and moisture; prone to hydrolysis in strong acid or alkaline environment, and decomposition when exposed to high temperature and strong light for a long time.
- Key Parameters: Density 1.6±0.1 g/cm3 (25°C, calculated); Refractive Index 1.590 (calculated); Flash Point 162.9±27.9°C (calculated); Purity ≥99.0% (HPLC); Water Content ≤0.5%; Loss on Drying ≤0.5%; Residue on Ignition ≤0.1%.
Uses
1-(Benzo[d][1,3]dioxol-5-yl)-2-bromopropan-1-one is a synthetic organic ketone compound, mainly used as a pharmaceutical intermediate, fine chemical raw material and organic synthesis intermediate, widely applied in pharmaceutical, chemical synthesis and biochemical research fields. In pharmaceutical industry, it is an important intermediate for the synthesis of various pharmaceutical derivatives, and is often used in the research and development of drugs related to heterocyclic compounds. In organic synthesis, it is used as a key raw material for the synthesis of heterocyclic compounds, dyestuff intermediates and pesticide intermediates, providing important support for the synthesis of fine chemicals. In biochemical research, it is used as a research reagent for organic synthesis reaction mechanism and material structure analysis, and is suitable for laboratory research and small-batch production. Additionally, it can be customized according to research and production needs, and is widely used in the field of fine chemical industry worldwide.
Packaging & Storage
Packaging: Laboratory grade: 100mg/1g amber glass bottles or aluminum foil bags with Teflon seals to prevent moisture absorption and light exposure. Industrial grade: 1kg/bag, 25kg fiber drums with double-layer PE liners, labeled with "Hygroscopic", "Keep Away from Heat" and GHS hazard information (GHS07, H302, H315, H319, H335). Storage: Store in a cool, dry, ventilated warehouse at room temperature below 25°C, relative humidity ≤65%; keep tightly closed to prevent moisture absorption and air contamination; separate from strong acids, bases and oxidizing agents; avoid mixing with toxic and harmful substances; shelf life 24 months under recommended conditions. Handle with gloves, goggles, and dust-proof protective clothing; use in ventilated areas to avoid dust inhalation and skin contact; wash skin thoroughly after contact; if splashed into eyes, rinse with flowing water for 10-15 minutes and seek medical help; if there is a leakage, collect with clean tools and properly dispose of waste; do not ingest; store away from heat sources and open flames; avoid transportation under high temperature and strong light.
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