Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: L-Proline
CAS Number: 147-85-3
Alias: L-Pyrrolidine-2-carboxylic acid
Molecular Formula: C5H9NO2
Molecular Weight: 115.13
IUPAC Name: (2S)-pyrrolidine-2-carboxylic acid
Structural Information
- Structure Type: Natural cyclic chiral amino acid
- Structural Features: Five-membered pyrrolidine ring structure, secondary amine group, chiral carboxylic acid, important component of collagen protein
Physical & Chemical Properties
- Appearance: White crystalline powder
- Odor: Odorless, slight sweet taste
- Melting Point: 220–222 °C (decomposes)
- Specific Rotation: [α]20/D -84° ~ -86° (c=4, water)
- Solubility: Freely soluble in water; soluble in ethanol; insoluble in ether, acetone
- Stability: Stable under normal sealed storage; heat-resistant in neutral environment; reacts with aldehydes to form Schiff base
Synthesis & Applications
Production Method
Hydrolysis of animal collagen protein, then decolorization, ion exchange and recrystallization purification.
Main Applications
- Food additive: Nutrition fortifier, flavor enhancer for food and beverage
- Health care raw material: Collagen synthesis supplement, joint care nutritional ingredient
- Peptide synthesis raw material: Chiral building block for polypeptide drug production
- Cosmetic raw material: Moisturizing anti-aging skincare additive
Safety & Storage Instructions
- Hazard Classification: Low toxicity, non-irritant
- Personal Protection: Ordinary dust mask and gloves for powder operation
- Storage Condition: Hermetically sealed, cool dry ventilated warehouse, moisture-proof
- Transportation: General goods, avoid dampness and extrusion
Quality Specifications
- Purity: ≥99.0% (HPLC)
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Heavy Metal (Pb): ≤10 ppm
Information Summary Table
| Item | Specification |
| CAS Number | 147-85-3 |
| Product Name | L-Proline |
| Synonym | L-Pyrrolidine-2-carboxylic acid |
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.13 |
| Appearance | White crystalline powder |
| Melting Point | 220–222 °C (decompose) |
| Solubility | Easily soluble in water |
| Purity Standard | ≥99.0% |
| Storage Condition | Sealed cool dry warehouse, moisture-proof |
| Hazard Property | Low toxicity, non-irritant |
| Main Usage | Peptide synthesis block, food nutrition fortifier, collagen health raw material |
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