Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: 2,2'-Dithiosalicylic acid
CAS Number: 119-80-2
Alias: DTSA, 2,2'-Dithiobisbenzoic acid
Molecular Formula: C14H10O4S2
Molecular Weight: 306.35
IUPAC Name: 2-[(2-carboxyphenyl)disulfanyl]benzoic acid
Structural Information
- Structure Type: Aromatic disulfide dibasic carboxylic acid
- Structural Features: Two salicylic acid fragments linked by disulfide bond (-S-S-), two ortho-carboxyl groups, easy to break disulfide bond under reduction condition
Physical & Chemical Properties
- Appearance: Light yellow crystalline powder
- Odor: Slight sulfur odor
- Melting Point: 240–242 °C (decomposes)
- Solubility: Insoluble in water; soluble in ethanol, methanol, alkaline aqueous solution, slightly soluble in acetone
- Stability: Stable under dry dark storage; disulfide bond cleaved by reducing agent; decomposes under strong heating; reacts with alkali to form soluble salt
Synthesis & Applications
Production Method
Oxidation of thiosalicylic acid with hydrogen peroxide, then recrystallization purification.
Main Applications
- Analytical reagent: Chromogenic reagent for metal ion detection
- Pharmaceutical intermediate: Raw material for thiol-containing drugs
- Rubber additive: Crosslinking auxiliary agent
- Biochemical research reagent: Disulfide probe for protein modification
Safety & Storage Instructions
- Hazard Classification: Mild irritant to skin, eyes and respiratory tract
- Personal Protection: Dust mask, nitrile gloves and goggles during powder operation
- Storage Condition: Hermetically sealed, cool dry dark warehouse, avoid reducing agents
- Transportation: General industrial chemical, avoid dampness and high temperature
Quality Specifications
- Purity: ≥99.0% (HPLC)
- Loss on Drying: ≤0.3%
- Residue on Ignition: ≤0.1%
- Single unknown impurity: ≤0.1%
Information Summary Table
| Item | Specification |
| CAS Number | 119-80-2 |
| Product Name | 2,2'-Dithiosalicylic acid |
| Synonym | DTSA, 2,2'-Dithiobisbenzoic acid |
| Molecular Formula | C14H10O4S2 |
| Molecular Weight | 306.35 |
| Appearance | Light yellow crystalline powder |
| Melting Point | 240–242 °C (decompose) |
| Solubility | Soluble in alcohol and alkali water, insoluble in water |
| Purity Standard | ≥99.0% |
| Storage Condition | Sealed cool dry place, isolate reducing substances |
| Hazard Property | Mild skin, eye and respiratory irritant |
| Main Usage | Metal analytical reagent, pharmaceutical intermediate, protein research probe |
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