Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Thiamine chloride
CAS Number: 59-43-8
Alias: Vitamin B1 hydrochloride, Thiamine HCl
Molecular Formula: C12H17ClN4OS·HCl
Molecular Weight: 337.27
IUPAC Name: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride hydrochloride
Structural Information
- Structure Type: Thiazole-pyrimidine heterocyclic quaternary ammonium hydrochloride, water-soluble B vitamin
- Structural Features: Fused pyrimidine and thiazole ring skeleton, quaternary ammonium cation combined with two chloride ions, easily forms coenzyme thiamine pyrophosphate in vivo
Physical & Chemical Properties
- Appearance: White crystalline powder
- Odor: Slight characteristic odor, bitter taste
- Melting Point: Decomposes above 248 °C
- Solubility: Freely soluble in water; slightly soluble in ethanol; insoluble in ether, benzene
- Stability: Stable under dry sealed storage; easily decomposed and discolored under light and alkaline conditions; heat-resistant in weak acid environment
Synthesis & Applications
Production Method
Chemical total synthesis via pyrimidine and thiazole fragment condensation, then salt formation with hydrochloric acid and recrystallization refining.
Main Applications
- Food fortifier: Vitamin B1 supplement for flour, beverage, dairy and functional food
- Feed additive: Nutritional additive for livestock and poultry feed
- Pharmaceutical raw material: API for treating vitamin B1 deficiency, neuritis and fatigue
- Biochemical reagent: Cell culture medium nutrient supplement
Safety & Storage Instructions
- Hazard Classification: Low toxicity, mild eye irritant
- Personal Protection: Ordinary dust mask and gloves during powder operation
- Storage Condition: Hermetically sealed, cool dark dry warehouse, strictly light-proof and moisture-proof
- Transportation: General goods, avoid dampness, high temperature and direct sunlight
Quality Specifications
- Purity: 98.5%–101.5%
- Loss on Drying: ≤0.5%
- Residue on Ignition: ≤0.1%
- Heavy Metal (Pb): ≤10 ppm
Information Summary Table
| Item | Specification |
| CAS Number | 59-43-8 |
| Product Name | Thiamine chloride |
| Synonym | Vitamin B1 hydrochloride |
| Molecular Formula | C12H17ClN4OS·HCl |
| Molecular Weight | 337.27 |
| Appearance | White crystalline powder |
| Solubility | Easily soluble in water |
| Purity Standard | 98.5%–101.5% |
| Storage Condition | Sealed cool dark warehouse, light & moisture resistant |
| Hazard Property | Low toxicity, slight eye irritant |
| Main Usage | Food vitamin fortifier, feed additive, vitamin B1 deficiency treatment API |
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