Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Papain
CAS Number: 9001-73-4
Alias: Papaya peptidase I, Papaya protease
Molecular Formula: Macromolecular protein enzyme (main monomer C20H30N6O6S, natural polymer mixture)
Average Molecular Weight: ~23000 Da
IUPAC Name: Not applicable (natural protein enzyme mixture)
Structural Information
- Structure Type: Natural thiol protease extracted from papaya latex
- Structural Features: Single-chain polypeptide containing cysteine active center; sulfhydryl group is the core catalytic site, easily inactivated by oxidants and heavy metal ions
Physical & Chemical Properties
- Appearance: White to light beige powder
- Odor: Slight characteristic plant odor
- Solubility: Soluble in water and dilute salt solution; insoluble in ethanol, acetone, ether
- Optimum pH: 5.0–7.0; stable pH range 3.0–9.0
- Optimum temperature: 50–60 °C; irreversible deactivation above 85 °C
- Stability: Hygroscopic; stable under low temperature dry sealed storage; inhibited by heavy metals, hydrogen peroxide, strong oxidants; activated by reducing agents (cysteine, EDTA)
Synthesis & Applications
Production Method
Extracted and separated from fresh papaya fruit latex via filtration, ultrafiltration, desalination, freeze-drying or spray drying.
Main Applications
- Food industry: Meat tenderizer, beer/wine clarifier, biscuit dough modifier, protein hydrolysis raw material
- Cosmetic raw material: Exfoliating enzyme for skincare, keratin decomposing additive
- Pharmaceutical auxiliary: Digestive aid preparations, wound debridement enzyme
- Feed additive: Improve animal protein digestion and absorption efficiency
Safety & Storage Instructions
GHS Hazard Classification
- H315 Skin irritation
- H319 Serious eye irritation
- H334 May cause allergy or asthma symptoms if inhaled
Personal Protection
Dust-proof respirator, chemical goggles, nitrile gloves; operate in ventilated space to avoid enzyme dust inhalation
Storage Condition
Hermetically sealed moisture-proof container, 2–8°C cool dry warehouse; isolate oxidants, heavy metal salts
Transportation
General biological raw material; avoid high temperature, dampness and package breakage
Quality Specifications
- Enzyme activity: 100,000–1,000,000 U/g (customizable)
- Loss on Drying: ≤6.0%
- Heavy Metal (Pb): ≤10 ppm
- Arsenic: ≤2 ppm
Information Summary Table
| Item | Specification |
| CAS Number | 9001-73-4 |
| Product Name | Papain |
| Synonym | Papaya protease |
| Molecular Formula | Polypeptide macromolecule mixture |
| Molecular Weight | ~23000 Da |
| Appearance | Off-white fine powder |
| Solubility | Soluble in water, insoluble in organic solvents |
| Activity Standard | Custom enzyme activity grades |
| Storage Condition | Sealed low-temperature dry storage, away from oxidants |
| Hazard Property | Dust allergen, irritates skin, eyes and respiratory tract |
| Main Usage | Food tenderizing/clarifying agent, cosmetic exfoliating ingredient, digestive pharmaceutical raw material |
...
Product
