Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Docusate sodium
CAS Number: 577-11-7
Alias: Dioctyl sodium sulfosuccinate, DOSS
Molecular Formula: C20H37NaO7S
Molecular Weight: 444.56
IUPAC Name: sodium 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonate
Structural Information
- Structure Type: Anionic sulfosuccinate surfactant
- Structural Features: Succinic acid backbone with two 2-ethylhexyl ester side chains and sulfonate sodium group; strong hydrophilic-lipophilic balance, excellent wetting, emulsifying and penetrating performance
Physical & Chemical Properties
- Appearance: White or off-white waxy solid/powder
- Odor: Faint characteristic fatty ester odor
- Melting Point: 153–157 °C
- Solubility: Soluble in water, ethanol, methanol, acetone, mineral oil; insoluble in alkane solvents
- Stability: Stable under neutral and weak acidic conditions; hydrolyzes under strong acid or strong alkali heating; compatible with most nonionic and anionic surfactants, precipitates with cationic substances
Synthesis & Applications
Production Method
Maleic anhydride reacts with 2-ethylhexanol to form dioctyl maleate, followed by sulfonation with sodium bisulfite and purification.
Main Applications
- Pharmaceutical excipient: Oral laxative raw material, solubilizer for liquid oral preparations
- Industrial surfactant: Wetting agent for textile printing, pesticide emulsifier, paper deinking agent
- Cosmetic additive: Penetrating agent and emulsifier for creams and cleansing products
- Chemical auxiliary: Dispersant for coatings, ink wetting agent
Safety & Storage Instructions
GHS Hazard Classification
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Personal Protection
Chemical splash goggles, nitrile gloves, dust mask; operate in ventilated workshop
Storage Condition
Hermetically sealed container, cool dry warehouse; separate from strong acid, strong alkali and cationic surfactants
Transportation
General fine chemical, avoid high temperature and dampness
Quality Specifications
- Purity: ≥98.0% (HPLC)
- Loss on Drying: ≤0.5%
- pH (1% aqueous solution): 5.0–7.0
- Heavy Metal (Pb): ≤10 ppm
Information Summary Table
| Item | Specification |
| CAS Number | 577-11-7 |
| Product Name | Docusate sodium |
| Synonym | Dioctyl sodium sulfosuccinate, DOSS |
| Molecular Formula | C20H37NaO7S |
| Molecular Weight | 444.56 |
| Appearance | White waxy solid/powder |
| Melting Point | 153–157 °C |
| Solubility | Soluble in water and most polar organic solvents |
| Purity Standard | ≥98.0% |
| Storage Condition | Sealed cool dry storage, isolate strong acid/alkali/cationic surfactants |
| Hazard Property | Irritant to skin, eyes and respiratory tract |
| Main Usage | Pharmaceutical laxative & solubilizer, industrial wetting/emulsifying surfactant |
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