Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: Fenbendazole
CAS Number: 43210-67-9
Alias: Methyl 5-phenylthio-2-benzimidazolecarbamate
Molecular Formula: C15H13N3O2S
Molecular Weight: 299.35
IUPAC Name: methyl N-(5-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate
Structural Information
- Structure Type: Benzimidazole broad-spectrum anthelmintic
- Structural Features: Benzimidazole parent ring structure, phenylthio substituent at 5-position, methyl carbamate group at 2-position; inhibits parasite tubulin synthesis, blocks nutrient uptake of worms
Physical & Chemical Properties
- Appearance: White to off-white crystalline powder
- Odor: Odorless
- Melting Point: 233–234 °C (decomposes)
- Solubility: Almost insoluble in water; slightly soluble in methanol, ethanol; soluble in DMSO, DMF; insoluble in alkane solvents
- Stability: Stable under normal sealed storage; resistant to weak acid and neutral environment; easy hydrolysis under strong alkaline heating; light stable, non-hygroscopic
Synthesis & Applications
Production Method
O-phenylenediamine reacts with thiophenol derivative, cyclized to form benzimidazole skeleton, then carbamylation with methyl chloroformate, recrystallization purification.
Main Applications
- Veterinary API: Broad-spectrum deworming drug for livestock, poultry, pets; expels roundworms, tapeworms, flukes
- Feed additive: Premix raw material for animal deworming
- Biomedical research reagent: Anti-parasite experimental compound, tumor research tool substance
Safety & Storage Instructions
GHS Hazard Classification
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Personal Protection
Dust mask, chemical splash goggles, nitrile gloves; operate in ventilated workshop
Storage Condition
Hermetically sealed container, cool dry warehouse; isolate strong alkaline substances
Transportation
General veterinary raw material, avoid high temperature, dampness and direct sunlight
Quality Specifications
- Purity: ≥99.0% (HPLC)
- Loss on Drying: ≤0.3%
- Residue on Ignition: ≤0.1%
- Single unknown impurity: ≤0.10%
Information Summary Table
| Item | Specification |
| CAS Number | 43210-67-9 |
| Product Name | Fenbendazole |
| Synonym | Methyl 5-phenylthio-2-benzimidazolecarbamate |
| Molecular Formula | C15H13N3O2S |
| Molecular Weight | 299.35 |
| Appearance | White crystalline powder |
| Melting Point | 233–234°C (decompose) |
| Solubility | Insoluble in water, soluble in polar aprotic solvents |
| Purity Standard | ≥99.0% |
| Storage Condition | Sealed cool dry storage, separate from strong alkali |
| Hazard Property | Mild irritant to skin, eyes and respiratory tract |
| Main Usage | Veterinary broad-spectrum anthelmintic raw material, animal feed deworming premix intermediate |
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