Shandong Huashang Chemical Co., Ltd. is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shandong Huashang Chemical Co., Ltd. is located in Shan Dong Ji Nan China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.
Basic Information
Product Name: D-(+)-Pantothenic acid calcium salt
CAS Number: 137-08-6
Alias: Calcium D-pantothenate, Vitamin B5 Calcium
Molecular Formula: C18H32CaN2O10
Molecular Weight: 476.53
IUPAC Name: calcium bis[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]acetate
Structural Information
- Structure Type: Water-soluble B vitamin calcium salt
- Structural Features: Two D-pantothenic acid anions chelate with one calcium ion; contains pantolactone and β-alanine structural fragments, core component of coenzyme A in human metabolism
Physical & Chemical Properties
- Appearance: White crystalline powder
- Odor: Slight characteristic odor, bitter sweet taste
- Melting Point: 195–196 °C (decomposition)
- Specific Rotation: [α]D2? +24° ~ +28° (aqueous solution)
- Solubility: Freely soluble in water; slightly soluble in methanol; insoluble in ethanol, acetone, ether
- Stability: Hygroscopic; stable under weak acid and neutral conditions; decomposes under strong acid, strong alkali and high temperature to lose activity; sensitive to long-term strong light
Synthesis & Applications
Production Method
Condensation of D-pantolactone with β-alanine to generate D-pantothenic acid, neutralized with calcium hydroxide, recrystallized and dried.
Main Applications
- Pharmaceutical API: Vitamin B5 raw material for compound vitamin tablets, injections
- Food fortifier: Additive for dairy, beverage, cereal, functional health food
- Feed additive: Poultry, livestock, aquaculture feed nutritional supplement to promote growth
- Cosmetic raw material: Skin repairing, moisturizing, anti-dandruff care ingredient
Safety & Storage Instructions
GHS Hazard Classification
Low toxicity, Warning signal word
- H315 Dust irritates skin
- H319 Causes serious eye irritation
- H335 May irritate respiratory tract
Personal Protection
Dust mask, chemical goggles, nitrile gloves; operate in ventilated environment, avoid moisture absorption
Storage Condition
Hermetically sealed light-proof moisture-proof container, cool dry warehouse; isolate strong acid and alkali
Transportation
General food/pharmaceutical raw material; waterproof packaging, avoid sunlight and dampness
Quality Specifications
- Purity: 98.0%–102.0% (titration)
- Loss on Drying: ≤5.0%
- Residue on Ignition: 14.0%–16.0%
- Heavy Metal (Pb): ≤10 ppm
Information Summary Table
| Item | Specification |
| CAS Number | 137-08-6 |
| Product Name | D-(+)-Pantothenic acid calcium salt |
| Synonym | Calcium D-pantothenate, Calcium Vitamin B5 |
| Molecular Formula | C18H32CaN2O10 |
| Molecular Weight | 476.53 |
| Appearance | White hygroscopic crystalline powder |
| Melting Point | 195–196°C (decompose) |
| Solubility | Easily soluble in water |
| Purity Standard | 98.0%–102.0% |
| Storage Condition | Sealed light-proof moisture-proof cool storage, separate from acid/alkali |
| Hazard Property | Low toxicity, dust mild irritant to skin, eyes and respiratory tract |
| Main Usage | Vitamin pharmaceutical raw material, food/feed nutrition fortifier, skincare repair additive |
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